FABP12 protein (human) - STRING database

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FABP12

Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family (140 aa)

Predicted Functional Partners:

LIPE

0.905

FABP4

0.902

TDRD10

0.643

FABP6

0.636

FABP1

0.535

SLC5A12

0.479

ABCA6

0.474

ABCA13

0.468

ABCA5

0.464

GOT2

0.460

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA13	FABP12	ENSP00000411096	ENSP00000353650	ATP binding cassette subfamily A member 13	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	0.468
ABCA5	FABP12	ENSP00000376443	ENSP00000353650	ATP-binding cassette sub-family A member 5; May play a role in the processing of autolysosomes; Belongs to the ABC transporter superfamily. ABCA family	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	0.464
ABCA6	FABP12	ENSP00000284425	ENSP00000353650	ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	0.474
FABP1	FABP12	ENSP00000295834	ENSP00000353650	Fatty acid-binding protein, liver; Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	0.535
FABP1	FABP4	ENSP00000295834	ENSP00000256104	Fatty acid-binding protein, liver; Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	Fatty acid-binding protein, adipocyte; Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	0.969
FABP1	GOT2	ENSP00000295834	ENSP00000245206	Fatty acid-binding protein, liver; Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family	0.926
FABP1	LIPE	ENSP00000295834	ENSP00000244289	Fatty acid-binding protein, liver; Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	Hormone-sensitive lipase; In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production; Lipases	0.943
FABP12	ABCA13	ENSP00000353650	ENSP00000411096	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	ATP binding cassette subfamily A member 13	0.468
FABP12	ABCA5	ENSP00000353650	ENSP00000376443	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	ATP-binding cassette sub-family A member 5; May play a role in the processing of autolysosomes; Belongs to the ABC transporter superfamily. ABCA family	0.464
FABP12	ABCA6	ENSP00000353650	ENSP00000284425	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family	0.474
FABP12	FABP1	ENSP00000353650	ENSP00000295834	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	Fatty acid-binding protein, liver; Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	0.535
FABP12	FABP4	ENSP00000353650	ENSP00000256104	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	Fatty acid-binding protein, adipocyte; Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	0.902
FABP12	FABP6	ENSP00000353650	ENSP00000377549	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	Gastrotropin; Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order- deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	0.636
FABP12	GOT2	ENSP00000353650	ENSP00000245206	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family	0.460
FABP12	LIPE	ENSP00000353650	ENSP00000244289	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	Hormone-sensitive lipase; In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production; Lipases	0.905
FABP12	SLC5A12	ENSP00000353650	ENSP00000379326	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	Sodium-coupled monocarboxylate transporter 2; Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D- hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral uptake of lactate, wi [...]	0.479
FABP12	TDRD10	ENSP00000353650	ENSP00000357465	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	Tudor domain-containing protein 10; RNA binding motif containing	0.643
FABP4	FABP1	ENSP00000256104	ENSP00000295834	Fatty acid-binding protein, adipocyte; Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	Fatty acid-binding protein, liver; Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	0.969
FABP4	FABP12	ENSP00000256104	ENSP00000353650	Fatty acid-binding protein, adipocyte; Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	Fatty acid-binding protein 12; May play a role in lipid transport; Fatty acid binding protein family	0.902
FABP4	FABP6	ENSP00000256104	ENSP00000377549	Fatty acid-binding protein, adipocyte; Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	Gastrotropin; Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order- deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family	0.946

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