PGLYRP4 protein (human) - STRING database

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PGLYRP4

Peptidoglycan recognition protein 4; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity; Peptidoglycan recognition proteins (373 aa)

Predicted Functional Partners:

PGLYRP3

0.935

LCE3B

0.741

LCE1A

0.723

LCE3C

0.711

OR5D14

0.571

IVL

0.548

SPG7

0.510

LINGO4

0.468

CRCT1

0.464

LOR

0.457

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRCT1	IVL	ENSP00000357779	ENSP00000357753	Cysteine rich C-terminal 1	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	0.613
CRCT1	LINGO4	ENSP00000357779	ENSP00000357810	Cysteine rich C-terminal 1	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4; Leucine rich repeat and Ig domain containing 4	0.463
CRCT1	LOR	ENSP00000357779	ENSP00000357731	Cysteine rich C-terminal 1	Loricrin; Major keratinocyte cell envelope protein; Cornified envelope precursor family	0.426
CRCT1	PGLYRP4	ENSP00000357779	ENSP00000352672	Cysteine rich C-terminal 1	Peptidoglycan recognition protein 4; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity; Peptidoglycan recognition proteins	0.464
IVL	CRCT1	ENSP00000357753	ENSP00000357779	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Cysteine rich C-terminal 1	0.613
IVL	LCE1A	ENSP00000357753	ENSP00000334869	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum	0.955
IVL	LCE3B	ENSP00000357753	ENSP00000335358	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Late cornified envelope protein 3B; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	0.955
IVL	LCE3C	ENSP00000357753	ENSP00000334644	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Late cornified envelope protein 3C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	0.951
IVL	LOR	ENSP00000357753	ENSP00000357731	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Loricrin; Major keratinocyte cell envelope protein; Cornified envelope precursor family	0.993
IVL	PGLYRP3	ENSP00000357753	ENSP00000290722	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family	0.612
IVL	PGLYRP4	ENSP00000357753	ENSP00000352672	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Peptidoglycan recognition protein 4; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity; Peptidoglycan recognition proteins	0.548
LCE1A	IVL	ENSP00000334869	ENSP00000357753	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	0.955
LCE1A	LCE3B	ENSP00000334869	ENSP00000335358	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum	Late cornified envelope protein 3B; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	0.975
LCE1A	LCE3C	ENSP00000334869	ENSP00000334644	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum	Late cornified envelope protein 3C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	0.977
LCE1A	LOR	ENSP00000334869	ENSP00000357731	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum	Loricrin; Major keratinocyte cell envelope protein; Cornified envelope precursor family	0.963
LCE1A	PGLYRP3	ENSP00000334869	ENSP00000290722	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum	Peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family	0.744
LCE1A	PGLYRP4	ENSP00000334869	ENSP00000352672	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum	Peptidoglycan recognition protein 4; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity; Peptidoglycan recognition proteins	0.723
LCE3B	IVL	ENSP00000335358	ENSP00000357753	Late cornified envelope protein 3B; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	0.955
LCE3B	LCE1A	ENSP00000335358	ENSP00000334869	Late cornified envelope protein 3B; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum	0.975
LCE3B	LCE3C	ENSP00000335358	ENSP00000334644	Late cornified envelope protein 3B; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	Late cornified envelope protein 3C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	0.933

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