HAPLN3 protein (human) - STRING database

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HAPLN3

Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing (360 aa)

Predicted Functional Partners:

CCDC181

0.679

CLEC3B

0.599

CHSY1

0.595

SERPINB10

0.567

KRT17

0.566

STX1B

0.554

GREB1L

0.552

MOB3B

0.533

NUCB2

0.499

TMEM106C

0.496

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC181	HAPLN3	ENSP00000356780	ENSP00000352606	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids; Belongs to the CCDC181 family	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	0.679
CCDC181	MOB3B	ENSP00000356780	ENSP00000262244	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids; Belongs to the CCDC181 family	MOB kinase activator 3B; May regulate the activity of kinases; MOB kinase activators	0.668
CHSY1	HAPLN3	ENSP00000254190	ENSP00000352606	Chondroitin sulfate synthase 1; Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	0.595
CLEC3B	HAPLN3	ENSP00000296130	ENSP00000352606	Tetranectin; Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis; C-type lectin domain containing	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	0.599
GREB1L	HAPLN3	ENSP00000464162	ENSP00000352606	GREB1-like protein; Growth regulation by estrogen in breast cancer 1 like; Belongs to the GREB1 family	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	0.552
HAPLN3	CCDC181	ENSP00000352606	ENSP00000356780	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids; Belongs to the CCDC181 family	0.679
HAPLN3	CHSY1	ENSP00000352606	ENSP00000254190	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	Chondroitin sulfate synthase 1; Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling	0.595
HAPLN3	CLEC3B	ENSP00000352606	ENSP00000296130	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	Tetranectin; Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis; C-type lectin domain containing	0.599
HAPLN3	GREB1L	ENSP00000352606	ENSP00000464162	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	GREB1-like protein; Growth regulation by estrogen in breast cancer 1 like; Belongs to the GREB1 family	0.552
HAPLN3	KRT17	ENSP00000352606	ENSP00000308452	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	Keratin, type I cytoskeletal 17; Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a mark [...]	0.566
HAPLN3	MOB3B	ENSP00000352606	ENSP00000262244	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	MOB kinase activator 3B; May regulate the activity of kinases; MOB kinase activators	0.533
HAPLN3	NUCB2	ENSP00000352606	ENSP00000436455	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	Nucleobindin-2; Calcium-binding protein. May have a role in calcium homeostasis; EF-hand domain containing	0.499
HAPLN3	SERPINB10	ENSP00000352606	ENSP00000238508	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	Serpin B10; Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus; Serpin peptidase inhibitors	0.567
HAPLN3	STX1B	ENSP00000352606	ENSP00000215095	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	Syntaxin-1B; Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (By similarity); Belongs to the syntaxin family	0.554
HAPLN3	TMEM106C	ENSP00000352606	ENSP00000400471	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	Transmembrane protein 106C	0.496
KRT17	HAPLN3	ENSP00000308452	ENSP00000352606	Keratin, type I cytoskeletal 17; Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a mark [...]	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	0.566
MOB3B	CCDC181	ENSP00000262244	ENSP00000356780	MOB kinase activator 3B; May regulate the activity of kinases; MOB kinase activators	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids; Belongs to the CCDC181 family	0.668
MOB3B	HAPLN3	ENSP00000262244	ENSP00000352606	MOB kinase activator 3B; May regulate the activity of kinases; MOB kinase activators	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	0.533
NUCB2	HAPLN3	ENSP00000436455	ENSP00000352606	Nucleobindin-2; Calcium-binding protein. May have a role in calcium homeostasis; EF-hand domain containing	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	0.499
SERPINB10	HAPLN3	ENSP00000238508	ENSP00000352606	Serpin B10; Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus; Serpin peptidase inhibitors	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing	0.567

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