node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1orf116 | C1orf74 | ENSP00000352447 | ENSP00000294811 | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | UPF0739 protein C1orf74; Chromosome 1 open reading frame 74; Belongs to the UPF0739 family | 0.491 |
C1orf116 | C9orf152 | ENSP00000352447 | ENSP00000383456 | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | Uncharacterized protein C9orf152; Chromosome 9 open reading frame 152 | 0.497 |
C1orf116 | HOMER1 | ENSP00000352447 | ENSP00000334382 | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | Homer protein homolog 1; Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabo [...] | 0.795 |
C1orf116 | MAP10 | ENSP00000352447 | ENSP00000403208 | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | Microtubule-associated protein 10; Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis | 0.688 |
C1orf116 | MAP1S | ENSP00000352447 | ENSP00000325313 | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family | 0.559 |
C1orf116 | MAP6 | ENSP00000352447 | ENSP00000307093 | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | Microtubule-associated protein 6; Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity. Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with TMEM106B | 0.557 |
C1orf116 | MAP7 | ENSP00000352447 | ENSP00000482335 | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | Ensconsin; Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments; Belongs to the MAP7 family | 0.579 |
C1orf116 | MAP9 | ENSP00000352447 | ENSP00000310593 | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | Microtubule-associated protein 9; Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules | 0.626 |
C1orf116 | OS9 | ENSP00000352447 | ENSP00000318165 | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | Protein OS-9; Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4; MRH domain containing | 0.550 |
C1orf116 | PDZK1IP1 | ENSP00000352447 | ENSP00000294338 | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | PDZK1-interacting protein 1; May play an important role in tumor biology | 0.486 |
C1orf74 | C1orf116 | ENSP00000294811 | ENSP00000352447 | UPF0739 protein C1orf74; Chromosome 1 open reading frame 74; Belongs to the UPF0739 family | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | 0.491 |
C9orf152 | C1orf116 | ENSP00000383456 | ENSP00000352447 | Uncharacterized protein C9orf152; Chromosome 9 open reading frame 152 | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | 0.497 |
HOMER1 | C1orf116 | ENSP00000334382 | ENSP00000352447 | Homer protein homolog 1; Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabo [...] | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | 0.795 |
MAP10 | C1orf116 | ENSP00000403208 | ENSP00000352447 | Microtubule-associated protein 10; Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | 0.688 |
MAP10 | MAP1S | ENSP00000403208 | ENSP00000325313 | Microtubule-associated protein 10; Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis | Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family | 0.759 |
MAP10 | MAP6 | ENSP00000403208 | ENSP00000307093 | Microtubule-associated protein 10; Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis | Microtubule-associated protein 6; Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity. Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with TMEM106B | 0.786 |
MAP10 | MAP7 | ENSP00000403208 | ENSP00000482335 | Microtubule-associated protein 10; Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis | Ensconsin; Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments; Belongs to the MAP7 family | 0.774 |
MAP10 | MAP9 | ENSP00000403208 | ENSP00000310593 | Microtubule-associated protein 10; Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis | Microtubule-associated protein 9; Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules | 0.858 |
MAP10 | PDZK1IP1 | ENSP00000403208 | ENSP00000294338 | Microtubule-associated protein 10; Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis | PDZK1-interacting protein 1; May play an important role in tumor biology | 0.664 |
MAP1S | C1orf116 | ENSP00000325313 | ENSP00000352447 | Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family | Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family | 0.559 |