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C9orf152 C9orf152 HOMER1 HOMER1 OS9 OS9 MAP9 MAP9 C1orf116 C1orf116 MAP10 MAP10 MAP7 MAP7 MAP6 MAP6 PDZK1IP1 PDZK1IP1 C1orf74 C1orf74 MAP1S MAP1S
"C1orf116" - Specifically androgen-regulated gene protein in Homo sapiens
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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C1orf116Specifically androgen-regulated gene protein; Putative androgen-specific receptor; Belongs to the SARG family (601 aa)    
Predicted Functional Partners:
HOMER1
Homer protein homolog 1; Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabo [...] (354 aa)
       
      0.795
MAP10
Microtubule-associated protein 10; Microtubule-associated protein (MAP) that plays a role in the regulation of cell division; promotes microtubule stability and participates in the organization of the spindle midzone and normal progress of cytokinesis (1047 aa)
           
  0.688
MAP9
Microtubule-associated protein 9; Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules (647 aa)
           
  0.626
MAP7
Ensconsin; Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments; Belongs to the MAP7 family (779 aa)
           
  0.579
MAP1S
Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family (1059 aa)
           
  0.559
MAP6
Microtubule-associated protein 6; Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity. Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with TMEM106B (813 aa)
           
  0.557
OS9
Protein OS-9; Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4; MRH domain containing (667 aa)
           
  0.550
C9orf152
Uncharacterized protein C9orf152; Chromosome 9 open reading frame 152 (239 aa)
           
  0.497
C1orf74
UPF0739 protein C1orf74; Chromosome 1 open reading frame 74; Belongs to the UPF0739 family (269 aa)
           
  0.491
PDZK1IP1
PDZK1-interacting protein 1; May play an important role in tumor biology (114 aa)
     
   
  0.486
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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