node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C18orf21 | KLHL14 | ENSP00000465517 | ENSP00000352314 | UPF0711 protein C18orf21; Chromosome 18 open reading frame 21 | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | 0.562 |
C18orf21 | POP1 | ENSP00000465517 | ENSP00000385787 | UPF0711 protein C18orf21; Chromosome 18 open reading frame 21 | Ribonucleases P/MRP protein subunit POP1; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP | 0.768 |
FBXL17 | KLHL14 | ENSP00000437464 | ENSP00000352314 | F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | 0.697 |
FBXL17 | KLHL28 | ENSP00000437464 | ENSP00000379434 | F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins | Kelch-like protein 28; Kelch like family member 28; BTB domain containing | 0.579 |
KIAA0247 | KLHL14 | ENSP00000344424 | ENSP00000352314 | Sushi domain-containing protein 6; May play a role in growth-suppressive activity and cell death. May be involved in the production of chemokine molecules in umbilical vein endothelial cells (HUVECs) cultured in THP1 monocyte LPS-induced medium. Plays a role in preventing tumor onset (By similarity) | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | 0.704 |
KIAA0247 | SLMO1 | ENSP00000344424 | ENSP00000404700 | Sushi domain-containing protein 6; May play a role in growth-suppressive activity and cell death. May be involved in the production of chemokine molecules in umbilical vein endothelial cells (HUVECs) cultured in THP1 monocyte LPS-induced medium. Plays a role in preventing tumor onset (By similarity) | PRELI domain containing protein 3A; In vitro, the TRIAP1-PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space. Phosphatidic acid import is required for cardiolipin (CL) synthesis in the mitochondrial inner membrane; Belongs to the slowmo family | 0.658 |
KIAA0247 | UCK2 | ENSP00000344424 | ENSP00000356853 | Sushi domain-containing protein 6; May play a role in growth-suppressive activity and cell death. May be involved in the production of chemokine molecules in umbilical vein endothelial cells (HUVECs) cultured in THP1 monocyte LPS-induced medium. Plays a role in preventing tumor onset (By similarity) | Uridine-cytidine kinase 2; Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4- thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)- benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5- methylcytidine, and N(4)-anisoylcytidine; Belongs to the uridine kinase family | 0.554 |
KLHL14 | C18orf21 | ENSP00000352314 | ENSP00000465517 | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | UPF0711 protein C18orf21; Chromosome 18 open reading frame 21 | 0.562 |
KLHL14 | FBXL17 | ENSP00000352314 | ENSP00000437464 | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins | 0.697 |
KLHL14 | KIAA0247 | ENSP00000352314 | ENSP00000344424 | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | Sushi domain-containing protein 6; May play a role in growth-suppressive activity and cell death. May be involved in the production of chemokine molecules in umbilical vein endothelial cells (HUVECs) cultured in THP1 monocyte LPS-induced medium. Plays a role in preventing tumor onset (By similarity) | 0.704 |
KLHL14 | KLHL28 | ENSP00000352314 | ENSP00000379434 | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | Kelch-like protein 28; Kelch like family member 28; BTB domain containing | 0.823 |
KLHL14 | NUDCD3 | ENSP00000352314 | ENSP00000347626 | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | NudC domain containing 3 | 0.603 |
KLHL14 | POP1 | ENSP00000352314 | ENSP00000385787 | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | Ribonucleases P/MRP protein subunit POP1; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. Also a component of RNase MRP | 0.587 |
KLHL14 | SLMO1 | ENSP00000352314 | ENSP00000404700 | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | PRELI domain containing protein 3A; In vitro, the TRIAP1-PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space. Phosphatidic acid import is required for cardiolipin (CL) synthesis in the mitochondrial inner membrane; Belongs to the slowmo family | 0.700 |
KLHL14 | TOR1A | ENSP00000352314 | ENSP00000345719 | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | Torsin-1A; Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular traffickin [...] | 0.759 |
KLHL14 | TOR1AIP2 | ENSP00000352314 | ENSP00000356584 | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | Torsin-1A-interacting protein 2; Required for endoplasmic reticulum integrity. Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope as well as induces TOR1A, TOR1B and TOR3A ATPase activity; Belongs to the TOR1AIP family | 0.589 |
KLHL14 | UCK2 | ENSP00000352314 | ENSP00000356853 | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | Uridine-cytidine kinase 2; Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4- thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)- benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5- methylcytidine, and N(4)-anisoylcytidine; Belongs to the uridine kinase family | 0.563 |
KLHL28 | FBXL17 | ENSP00000379434 | ENSP00000437464 | Kelch-like protein 28; Kelch like family member 28; BTB domain containing | F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins | 0.579 |
KLHL28 | KLHL14 | ENSP00000379434 | ENSP00000352314 | Kelch-like protein 28; Kelch like family member 28; BTB domain containing | Kelch-like protein 14; Kelch like family member 14; BTB domain containing | 0.823 |
KLHL28 | NUDCD3 | ENSP00000379434 | ENSP00000347626 | Kelch-like protein 28; Kelch like family member 28; BTB domain containing | NudC domain containing 3 | 0.552 |