• Version:
  • 11.0 [archived version]
STRINGSTRING
RSC1A1 RSC1A1 FLYWCH2 FLYWCH2 ZNF720 ZNF720 WDR90 WDR90 KRTAP5-10 KRTAP5-10 C16orf52 C16orf52 FAM86C1 FAM86C1 RGPD6 RGPD6 METTL21A METTL21A NADSYN1 NADSYN1 RPS23 RPS23
"FAM86C1" - Protein FAM86C1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM86C1Protein FAM86C1; Family with sequence similarity 86 member C1 (165 aa)    
Predicted Functional Partners:
FLYWCH2
FLYWCH family member 2 (140 aa)
           
  0.560
C16orf52
Uncharacterized protein C16orf52; Chromosome 16 open reading frame 52 (167 aa)
           
  0.559
ZNF720
Putative protein ZNF720; Zinc finger protein 720; Zinc fingers C2H2-type (126 aa)
           
  0.556
WDR90
WD repeat-containing protein 90; WD repeat domain containing (1748 aa)
     
   
  0.495
NADSYN1
Glutamine-dependent NAD(+) synthetase; NAD synthetase 1; In the C-terminal section; belongs to the NAD synthetase family (706 aa)
           
  0.489
RGPD6
RANBP2-like and GRIP domain-containing protein 5/6; Tetratricopeptide repeat domain containing (1765 aa)
     
   
  0.483
RSC1A1
Regulatory solute carrier protein family 1 member 1; Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network (617 aa)
           
  0.477
METTL21A
Protein N-lysine methyltransferase METTL21A; Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates ’Lys-561’ in HSPA1, ’Lys- 564’ in HSPA2, ’Lys-585’ in HSPA5, ’Lys-563’ in HSPA6 and ’Lys- 561’ in HSPA8 (218 aa)
       
 
  0.473
KRTAP5-10
Keratin-associated protein 5-10; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins (202 aa)
           
  0.473
RPS23
40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (143 aa)
     
 
  0.472
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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