• Version:
  • 11.0 [archived version]
STRINGSTRING
PSG7 PSG7 C17orf58 C17orf58 GOLGA8A GOLGA8A GORASP1 GORASP1 USO1 USO1 GOLGA3 GOLGA3 GOLGB1 GOLGB1 GOLGA1 GOLGA1 GOLGA8B GOLGA8B GOLGA5 GOLGA5 GOLGA4 GOLGA4
"GOLGA8A" - Golgin subfamily A member 8A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GOLGA8AGolgin subfamily A member 8A; May be involved in maintaining Golgi structure (603 aa)    
Predicted Functional Partners:
GOLGB1
Golgin subfamily B member 1; May participate in forming intercisternal cross-bridges of the Golgi complex (3269 aa)
     
 
  0.665
GOLGA3
Golgin subfamily A member 3; Golgi auto-antigen; probably involved in maintaining Golgi structure (1498 aa)
     
   
  0.603
GOLGA4
Golgin subfamily A member 4; May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1 (2243 aa)
     
   
  0.590
GOLGA1
Golgin subfamily A member 1; Probably involved in maintaining Golgi structure (767 aa)
     
   
  0.584
GOLGA5
Golgin subfamily A member 5; Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport (731 aa)
           
  0.564
GOLGA8B
Golgin subfamily A member 8B; May be involved in maintaining Golgi structure; Belongs to the GOLGA8 family (603 aa)
     
   
0.554
USO1
General vesicular transport factor p115; General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity; Armadillo-like helical domain containing (962 aa)
       
 
  0.551
GORASP1
Golgi reassembly-stacking protein 1; Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity- its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis (By similarity). Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes; PDZ domain containing (440 aa)
     
 
  0.498
C17orf58
UPF0450 protein C17orf58; Chromosome 17 open reading frame 58 (97 aa)
           
  0.473
PSG7
Pregnancy specific beta-1-glycoprotein 7; Belongs to the immunoglobulin superfamily. CEA family (419 aa)
           
  0.450
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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