• Version:
  • 11.0 [archived version]
STRINGSTRING
SFTA3 SFTA3 DPCR1 DPCR1 SFTPA1 SFTPA1 EGFL8 EGFL8 ENSG00000248167 ENSG00000248167 SFTA2 SFTA2 STK19 STK19 CBWD2 CBWD2 RSPH1 RSPH1 NRM NRM ABCF1 ABCF1
"SFTA2" - Surfactant-associated protein 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
SFTA2Surfactant-associated protein 2; Putative surfactant protein (78 aa)    
Predicted Functional Partners:
CBWD2
COBW domain containing 2; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily (395 aa)
       
      0.692
SFTA3
Surfactant-associated protein 3; Surfactant associated 3 (94 aa)
     
   
  0.658
DPCR1
Diffuse panbronchiolitis critical region 1 (1393 aa)
     
   
  0.580
SFTPA1
Pulmonary surfactant-associated protein A1; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages (By similarity); Belongs to the SFTPA family (263 aa)
     
   
  0.510
NRM
Nurim (262 aa)
           
  0.510
ABCF1
ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis; ATP binding cassette subfamily F (845 aa)
           
  0.503
EGFL8
Epidermal growth factor-like protein 8; EGF like domain multiple 8 (293 aa)
           
  0.490
RSPH1
Radial spoke head 1 homolog; May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes (309 aa)
           
  0.486
ENSG00000248167
Ribonuclease P protein subunit p21; TRIM39-RPP21 readthrough (503 aa)
           
  0.478
STK19
Serine/threonine-protein kinase 19; Seems to be a protein kinase. In vitro it can phosphorylate casein-alpha on serine and threonine residues and histones on serine residues (368 aa)
           
  0.477
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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