| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FRMPD2 | PBLD | ENSP00000363317 | ENSP00000351619 | FERM and PDZ domain-containing protein 2; May play a role in the regulation of tight junction formation. Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2); FERM domain containing | Phenazine biosynthesis like protein domain containing | 0.588 |
| LARP6 | PBLD | ENSP00000299213 | ENSP00000351619 | La-related protein 6; Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5’ UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9; La ribonucleoprotein domain containing | Phenazine biosynthesis like protein domain containing | 0.510 |
| LARP6 | PIGN | ENSP00000299213 | ENSP00000350263 | La-related protein 6; Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5’ UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9; La ribonucleoprotein domain containing | GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). May act as suppressor of replication stress and chromosome missegregation; Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily | 0.474 |
| LARP6 | STRAP | ENSP00000299213 | ENSP00000392270 | La-related protein 6; Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5’ UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9; La ribonucleoprotein domain containing | Serine-threonine kinase receptor-associated protein; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICl [...] | 0.770 |
| MYPN | PBLD | ENSP00000351790 | ENSP00000351619 | Myopalladin; Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines; Belongs to the myotilin/palladin family | Phenazine biosynthesis like protein domain containing | 0.724 |
| MYPN | RUFY2 | ENSP00000351790 | ENSP00000373420 | Myopalladin; Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines; Belongs to the myotilin/palladin family | RUN and FYVE domain containing 2; Zinc fingers FYVE-type | 0.526 |
| MYPN | SLC25A16 | ENSP00000351790 | ENSP00000476815 | Myopalladin; Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines; Belongs to the myotilin/palladin family | Graves disease carrier protein; Required for the accumulation of coenzyme A in the mitochondrial matrix; Solute carriers | 0.406 |
| PBLD | FRMPD2 | ENSP00000351619 | ENSP00000363317 | Phenazine biosynthesis like protein domain containing | FERM and PDZ domain-containing protein 2; May play a role in the regulation of tight junction formation. Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2); FERM domain containing | 0.588 |
| PBLD | LARP6 | ENSP00000351619 | ENSP00000299213 | Phenazine biosynthesis like protein domain containing | La-related protein 6; Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5’ UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9; La ribonucleoprotein domain containing | 0.510 |
| PBLD | MYPN | ENSP00000351619 | ENSP00000351790 | Phenazine biosynthesis like protein domain containing | Myopalladin; Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines; Belongs to the myotilin/palladin family | 0.724 |
| PBLD | PIGN | ENSP00000351619 | ENSP00000350263 | Phenazine biosynthesis like protein domain containing | GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). May act as suppressor of replication stress and chromosome missegregation; Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily | 0.501 |
| PBLD | PLEKHS1 | ENSP00000351619 | ENSP00000358316 | Phenazine biosynthesis like protein domain containing | Pleckstrin homology domain containing S1 | 0.685 |
| PBLD | RUFY2 | ENSP00000351619 | ENSP00000373420 | Phenazine biosynthesis like protein domain containing | RUN and FYVE domain containing 2; Zinc fingers FYVE-type | 0.709 |
| PBLD | SLC25A16 | ENSP00000351619 | ENSP00000476815 | Phenazine biosynthesis like protein domain containing | Graves disease carrier protein; Required for the accumulation of coenzyme A in the mitochondrial matrix; Solute carriers | 0.629 |
| PBLD | STRAP | ENSP00000351619 | ENSP00000392270 | Phenazine biosynthesis like protein domain containing | Serine-threonine kinase receptor-associated protein; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICl [...] | 0.952 |
| PBLD | TMEM50A | ENSP00000351619 | ENSP00000363478 | Phenazine biosynthesis like protein domain containing | Transmembrane protein 50A | 0.617 |
| PBLD | ZRANB1 | ENSP00000351619 | ENSP00000352676 | Phenazine biosynthesis like protein domain containing | Ubiquitin thioesterase ZRANB1; Specifically hydrolyzes ’Lys-29’-linked and ’Lys-33’- linked diubiquitin. Also cleaves ’Lys-63’-linked chains, but with 40-fold less efficiency compared to ’Lys-29’-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling; Belongs to the peptidase C64 family | 0.540 |
| PIGN | LARP6 | ENSP00000350263 | ENSP00000299213 | GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). May act as suppressor of replication stress and chromosome missegregation; Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily | La-related protein 6; Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5’ UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9; La ribonucleoprotein domain containing | 0.474 |
| PIGN | PBLD | ENSP00000350263 | ENSP00000351619 | GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). May act as suppressor of replication stress and chromosome missegregation; Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily | Phenazine biosynthesis like protein domain containing | 0.501 |
| PLEKHS1 | PBLD | ENSP00000358316 | ENSP00000351619 | Pleckstrin homology domain containing S1 | Phenazine biosynthesis like protein domain containing | 0.685 |
