C19orf60 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

C19orf60

Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60 (201 aa)

Predicted Functional Partners:

CRLF1

0.804

SMIM7

0.672

ANKRD35

0.640

FAM63A

0.577

CLCF1

0.572

RPL26L1

0.536

FAM53C

0.532

KBTBD2

0.521

WBP5

0.517

DNTTIP1

0.514

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD35	C19orf60	ENSP00000347802	ENSP00000351422	Ankyrin repeat domain-containing protein 35; Ankyrin repeat domain containing	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	0.640
ANKRD35	FAM63A	ENSP00000347802	ENSP00000354669	Ankyrin repeat domain-containing protein 35; Ankyrin repeat domain containing	Ubiquitin carboxyl-terminal hydrolase MINDY-1; Hydrolase that can specifically remove ’Lys-48’-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover; Belongs to the peptidase MINDY family. FAM63 subfamily	0.784
ANKRD35	SMIM7	ENSP00000347802	ENSP00000351569	Ankyrin repeat domain-containing protein 35; Ankyrin repeat domain containing	Small integral membrane protein 7	0.640
C19orf60	ANKRD35	ENSP00000351422	ENSP00000347802	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	Ankyrin repeat domain-containing protein 35; Ankyrin repeat domain containing	0.640
C19orf60	CLCF1	ENSP00000351422	ENSP00000309338	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	Cardiotrophin-like cytokine factor 1; Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor; Interleukin 6 type cytokine family	0.572
C19orf60	CRLF1	ENSP00000351422	ENSP00000376188	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	Cytokine receptor-like factor 1; Cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development; Fibronectin type III domain containing	0.804
C19orf60	DNTTIP1	ENSP00000351422	ENSP00000361705	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	Deoxynucleotidyltransferase terminal-interacting protein 1; Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5’- GNTGCATG-3’ following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA	0.514
C19orf60	FAM53C	ENSP00000351422	ENSP00000239906	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	Protein FAM53C; Family with sequence similarity 53 member C	0.532
C19orf60	FAM63A	ENSP00000351422	ENSP00000354669	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	Ubiquitin carboxyl-terminal hydrolase MINDY-1; Hydrolase that can specifically remove ’Lys-48’-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover; Belongs to the peptidase MINDY family. FAM63 subfamily	0.577
C19orf60	KBTBD2	ENSP00000351422	ENSP00000302586	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	Kelch repeat and BTB domain containing 2	0.521
C19orf60	RPL26L1	ENSP00000351422	ENSP00000428223	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family	0.536
C19orf60	SMIM7	ENSP00000351422	ENSP00000351569	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	Small integral membrane protein 7	0.672
C19orf60	WBP5	ENSP00000351422	ENSP00000361745	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	Transcription elongation factor A protein-like 9; May be involved in transcriptional regulation	0.517
CLCF1	C19orf60	ENSP00000309338	ENSP00000351422	Cardiotrophin-like cytokine factor 1; Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor; Interleukin 6 type cytokine family	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	0.572
CLCF1	CRLF1	ENSP00000309338	ENSP00000376188	Cardiotrophin-like cytokine factor 1; Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor; Interleukin 6 type cytokine family	Cytokine receptor-like factor 1; Cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development; Fibronectin type III domain containing	0.993
CRLF1	C19orf60	ENSP00000376188	ENSP00000351422	Cytokine receptor-like factor 1; Cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development; Fibronectin type III domain containing	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	0.804
CRLF1	CLCF1	ENSP00000376188	ENSP00000309338	Cytokine receptor-like factor 1; Cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development; Fibronectin type III domain containing	Cardiotrophin-like cytokine factor 1; Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor; Interleukin 6 type cytokine family	0.993
DNTTIP1	C19orf60	ENSP00000361705	ENSP00000351422	Deoxynucleotidyltransferase terminal-interacting protein 1; Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5’- GNTGCATG-3’ following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA	Uncharacterized protein C19orf60; Chromosome 19 open reading frame 60	0.514
DNTTIP1	FAM53C	ENSP00000361705	ENSP00000239906	Deoxynucleotidyltransferase terminal-interacting protein 1; Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5’- GNTGCATG-3’ following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA	Protein FAM53C; Family with sequence similarity 53 member C	0.515
DNTTIP1	KBTBD2	ENSP00000361705	ENSP00000302586	Deoxynucleotidyltransferase terminal-interacting protein 1; Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5’- GNTGCATG-3’ following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA	Kelch repeat and BTB domain containing 2	0.489

page 1 of 3

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2020

Credits

Access

Info

About