| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C1orf53 | TMA16 | ENSP00000356363 | ENSP00000351380 | Uncharacterized protein C1orf53; Chromosome 1 open reading frame 53 | Translation machinery associated 16 homolog | 0.587 |
| C4orf27 | TMA16 | ENSP00000406598 | ENSP00000351380 | Histone PARylation factor 1; Acts as a cofactor for serine ADP-ribosylation by conferring serine specificity on PARP1 and PARP2- interacts with PARP1 and PARP1 and is able to change amino acid specificity toward serine. Promotes histone serine ADP- ribosylation in response to DNA damage, limiting DNA damage- induced PARP1 hyper-automodification, and ensuring genome stability | Translation machinery associated 16 homolog | 0.551 |
| C4orf27 | TMA7 | ENSP00000406598 | ENSP00000397843 | Histone PARylation factor 1; Acts as a cofactor for serine ADP-ribosylation by conferring serine specificity on PARP1 and PARP2- interacts with PARP1 and PARP1 and is able to change amino acid specificity toward serine. Promotes histone serine ADP- ribosylation in response to DNA damage, limiting DNA damage- induced PARP1 hyper-automodification, and ensuring genome stability | Translation machinery associated 7 homolog | 0.485 |
| FUBP1 | HMCES | ENSP00000359804 | ENSP00000372955 | Far upstream element-binding protein 1; Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription | Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; Specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction | 0.500 |
| FUBP1 | LYAR | ENSP00000359804 | ENSP00000345917 | Far upstream element-binding protein 1; Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription | Cell growth-regulating nucleolar protein; Zinc fingers C2HC-type | 0.408 |
| FUBP1 | TMA16 | ENSP00000359804 | ENSP00000351380 | Far upstream element-binding protein 1; Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription | Translation machinery associated 16 homolog | 0.588 |
| HMCES | FUBP1 | ENSP00000372955 | ENSP00000359804 | Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; Specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction | Far upstream element-binding protein 1; Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription | 0.500 |
| HMCES | LYAR | ENSP00000372955 | ENSP00000345917 | Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; Specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction | Cell growth-regulating nucleolar protein; Zinc fingers C2HC-type | 0.578 |
| HMCES | OGFOD1 | ENSP00000372955 | ENSP00000457258 | Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; Specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction | Prolyl 3-hydroxylase OGFOD1; Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of ’Pro-62’ of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation; Belongs to the TPA1 family | 0.543 |
| HMCES | SMEK2 | ENSP00000372955 | ENSP00000483228 | Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; Specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction | Serine/threonine-protein phosphatase 4 regulatory subunit 3B; Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers | 0.502 |
| HMCES | THYN1 | ENSP00000372955 | ENSP00000341657 | Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; Specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction | Thymocyte nuclear protein 1; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC | 0.599 |
| HMCES | TMA16 | ENSP00000372955 | ENSP00000351380 | Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; Specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction | Translation machinery associated 16 homolog | 0.723 |
| LYAR | FUBP1 | ENSP00000345917 | ENSP00000359804 | Cell growth-regulating nucleolar protein; Zinc fingers C2HC-type | Far upstream element-binding protein 1; Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription | 0.408 |
| LYAR | HMCES | ENSP00000345917 | ENSP00000372955 | Cell growth-regulating nucleolar protein; Zinc fingers C2HC-type | Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; Specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction | 0.578 |
| LYAR | OGFOD1 | ENSP00000345917 | ENSP00000457258 | Cell growth-regulating nucleolar protein; Zinc fingers C2HC-type | Prolyl 3-hydroxylase OGFOD1; Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of ’Pro-62’ of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation; Belongs to the TPA1 family | 0.567 |
| LYAR | SMEK2 | ENSP00000345917 | ENSP00000483228 | Cell growth-regulating nucleolar protein; Zinc fingers C2HC-type | Serine/threonine-protein phosphatase 4 regulatory subunit 3B; Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers | 0.523 |
| LYAR | THYN1 | ENSP00000345917 | ENSP00000341657 | Cell growth-regulating nucleolar protein; Zinc fingers C2HC-type | Thymocyte nuclear protein 1; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC | 0.611 |
| LYAR | TMA16 | ENSP00000345917 | ENSP00000351380 | Cell growth-regulating nucleolar protein; Zinc fingers C2HC-type | Translation machinery associated 16 homolog | 0.764 |
| OGFOD1 | HMCES | ENSP00000457258 | ENSP00000372955 | Prolyl 3-hydroxylase OGFOD1; Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of ’Pro-62’ of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation; Belongs to the TPA1 family | Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; Specifically binds 5-hydroxymethylcytosine (5hmC)- containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction | 0.543 |
| OGFOD1 | LYAR | ENSP00000457258 | ENSP00000345917 | Prolyl 3-hydroxylase OGFOD1; Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of ’Pro-62’ of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation; Belongs to the TPA1 family | Cell growth-regulating nucleolar protein; Zinc fingers C2HC-type | 0.567 |
