| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC102A | GABRR1 | ENSP00000258214 | ENSP00000412673 | Coiled-coil domain containing 102A | Gamma-aminobutyric acid receptor subunit rho-1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission; Gamma-aminobutyric acid type A receptor subunits | 0.608 |
| CCDC102A | GALNT16 | ENSP00000258214 | ENSP00000336729 | Coiled-coil domain containing 102A | Polypeptide N-acetylgalactosaminyltransferase 16; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor; Polypeptide N-acetylgalactosaminyltransferases | 0.619 |
| CCDC102A | KIAA1671 | ENSP00000258214 | ENSP00000351207 | Coiled-coil domain containing 102A | Uncharacterized protein KIAA1671; KIAA1671 | 0.788 |
| CCDC102A | NEDD9 | ENSP00000258214 | ENSP00000368759 | Coiled-coil domain containing 102A | Enhancer of filamentation 1; Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphoryla [...] | 0.538 |
| CCDC102A | RPS6KA2 | ENSP00000258214 | ENSP00000427015 | Coiled-coil domain containing 102A | Ribosomal protein S6 kinase alpha-2; Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells; Mitogen-activated protein kinase-activated protein kinases | 0.522 |
| CREG2 | KIAA1671 | ENSP00000315203 | ENSP00000351207 | Protein CREG2; Cellular repressor of E1A stimulated genes 2 | Uncharacterized protein KIAA1671; KIAA1671 | 0.511 |
| CREG2 | LRRIQ4 | ENSP00000315203 | ENSP00000342188 | Protein CREG2; Cellular repressor of E1A stimulated genes 2 | Leucine rich repeats and IQ motif containing 4 | 0.514 |
| EFR3A | FAM134C | ENSP00000254624 | ENSP00000309432 | Protein EFR3 homolog A; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, EFR3A probably acts as the membrane-anchoring component. Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect | Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth; Belongs to the RETREG family | 0.424 |
| EFR3A | KIAA1671 | ENSP00000254624 | ENSP00000351207 | Protein EFR3 homolog A; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, EFR3A probably acts as the membrane-anchoring component. Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect | Uncharacterized protein KIAA1671; KIAA1671 | 0.486 |
| FAM134C | EFR3A | ENSP00000309432 | ENSP00000254624 | Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth; Belongs to the RETREG family | Protein EFR3 homolog A; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, EFR3A probably acts as the membrane-anchoring component. Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect | 0.424 |
| FAM134C | KIAA1671 | ENSP00000309432 | ENSP00000351207 | Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth; Belongs to the RETREG family | Uncharacterized protein KIAA1671; KIAA1671 | 0.536 |
| FAM134C | TULP4 | ENSP00000309432 | ENSP00000356064 | Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth; Belongs to the RETREG family | Tubby-related protein 4; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the TUB family | 0.401 |
| GABRR1 | CCDC102A | ENSP00000412673 | ENSP00000258214 | Gamma-aminobutyric acid receptor subunit rho-1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission; Gamma-aminobutyric acid type A receptor subunits | Coiled-coil domain containing 102A | 0.608 |
| GABRR1 | GALNT16 | ENSP00000412673 | ENSP00000336729 | Gamma-aminobutyric acid receptor subunit rho-1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission; Gamma-aminobutyric acid type A receptor subunits | Polypeptide N-acetylgalactosaminyltransferase 16; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor; Polypeptide N-acetylgalactosaminyltransferases | 0.579 |
| GABRR1 | KIAA1671 | ENSP00000412673 | ENSP00000351207 | Gamma-aminobutyric acid receptor subunit rho-1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission; Gamma-aminobutyric acid type A receptor subunits | Uncharacterized protein KIAA1671; KIAA1671 | 0.657 |
| GABRR1 | NEDD9 | ENSP00000412673 | ENSP00000368759 | Gamma-aminobutyric acid receptor subunit rho-1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission; Gamma-aminobutyric acid type A receptor subunits | Enhancer of filamentation 1; Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphoryla [...] | 0.543 |
| GABRR1 | RPS6KA2 | ENSP00000412673 | ENSP00000427015 | Gamma-aminobutyric acid receptor subunit rho-1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission; Gamma-aminobutyric acid type A receptor subunits | Ribosomal protein S6 kinase alpha-2; Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells; Mitogen-activated protein kinase-activated protein kinases | 0.540 |
| GALNT16 | CCDC102A | ENSP00000336729 | ENSP00000258214 | Polypeptide N-acetylgalactosaminyltransferase 16; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor; Polypeptide N-acetylgalactosaminyltransferases | Coiled-coil domain containing 102A | 0.619 |
| GALNT16 | GABRR1 | ENSP00000336729 | ENSP00000412673 | Polypeptide N-acetylgalactosaminyltransferase 16; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor; Polypeptide N-acetylgalactosaminyltransferases | Gamma-aminobutyric acid receptor subunit rho-1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission; Gamma-aminobutyric acid type A receptor subunits | 0.579 |
| GALNT16 | KIAA1671 | ENSP00000336729 | ENSP00000351207 | Polypeptide N-acetylgalactosaminyltransferase 16; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor; Polypeptide N-acetylgalactosaminyltransferases | Uncharacterized protein KIAA1671; KIAA1671 | 0.607 |
