LCA5L protein (human) - STRING database

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Score

LCA5L

Lebercilin-like protein; LCA5L, lebercilin like (670 aa)

Predicted Functional Partners:

PFDN5

0.692

PSMG1

0.636

SH3BGR

0.630

DSCR4

0.589

DSCR8

0.566

WRB

0.560

BRWD1

0.554

KRTAP21-2

0.551

ENSG00000249624

0.543

RSPH1

0.537

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRWD1	LCA5L	ENSP00000330753	ENSP00000351008	Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing	Lebercilin-like protein; LCA5L, lebercilin like	0.554
BRWD1	PSMG1	ENSP00000330753	ENSP00000329915	Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing	Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization	0.836
BRWD1	SH3BGR	ENSP00000330753	ENSP00000332513	Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing	SH3 domain-binding glutamic acid-rich protein; SH3 domain binding glutamate rich protein; Belongs to the SH3BGR family	0.630
BRWD1	WRB	ENSP00000330753	ENSP00000327716	Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing	Tail-anchored protein insertion receptor WRB; Receptor for ASNA1/TRC40-mediated insertion of tail- anchored (TA) proteins into the ER membrane; Belongs to the WRB/GET1 family	0.615
DSCR4	DSCR8	ENSP00000328676	ENSP00000350336	Down syndrome critical region 4	Down syndrome critical region 8	0.889
DSCR4	ENSG00000249624	ENSP00000328676	ENSP00000388223	Down syndrome critical region 4	annotation not available	0.472
DSCR4	KRTAP21-2	ENSP00000328676	ENSP00000334287	Down syndrome critical region 4	Keratin-associated protein 21-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins	0.473
DSCR4	LCA5L	ENSP00000328676	ENSP00000351008	Down syndrome critical region 4	Lebercilin-like protein; LCA5L, lebercilin like	0.589
DSCR4	PSMG1	ENSP00000328676	ENSP00000329915	Down syndrome critical region 4	Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization	0.629
DSCR4	RSPH1	ENSP00000328676	ENSP00000291536	Down syndrome critical region 4	Radial spoke head 1 homolog; May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes	0.444
DSCR4	SH3BGR	ENSP00000328676	ENSP00000332513	Down syndrome critical region 4	SH3 domain-binding glutamic acid-rich protein; SH3 domain binding glutamate rich protein; Belongs to the SH3BGR family	0.473
DSCR8	DSCR4	ENSP00000350336	ENSP00000328676	Down syndrome critical region 8	Down syndrome critical region 4	0.889
DSCR8	ENSG00000249624	ENSP00000350336	ENSP00000388223	Down syndrome critical region 8	annotation not available	0.428
DSCR8	KRTAP21-2	ENSP00000350336	ENSP00000334287	Down syndrome critical region 8	Keratin-associated protein 21-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins	0.430
DSCR8	LCA5L	ENSP00000350336	ENSP00000351008	Down syndrome critical region 8	Lebercilin-like protein; LCA5L, lebercilin like	0.566
DSCR8	PSMG1	ENSP00000350336	ENSP00000329915	Down syndrome critical region 8	Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization	0.505
ENSG00000249624	DSCR4	ENSP00000388223	ENSP00000328676	annotation not available	Down syndrome critical region 4	0.472
ENSG00000249624	DSCR8	ENSP00000388223	ENSP00000350336	annotation not available	Down syndrome critical region 8	0.428
ENSG00000249624	LCA5L	ENSP00000388223	ENSP00000351008	annotation not available	Lebercilin-like protein; LCA5L, lebercilin like	0.543
KRTAP21-2	DSCR4	ENSP00000334287	ENSP00000328676	Keratin-associated protein 21-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins	Down syndrome critical region 4	0.473

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