| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATP6V1A | GRAMD1C | ENSP00000273398 | ENSP00000350881 | V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation; Belongs to the ATPase alpha/beta chains family | GRAM domain containing 1C | 0.541 |
| ATP6V1A | GTPBP8 | ENSP00000273398 | ENSP00000373176 | V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation; Belongs to the ATPase alpha/beta chains family | GTP binding protein 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngB GTPase family | 0.560 |
| ATP6V1A | NAA50 | ENSP00000273398 | ENSP00000240922 | V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation; Belongs to the ATPase alpha/beta chains family | N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity- able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear- able to acetylate H4 in vitro, but this result has not been confirmed in vivo. [...] | 0.541 |
| CD151 | GRAMD1C | ENSP00000380565 | ENSP00000350881 | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney; Blood group antigens | GRAM domain containing 1C | 0.671 |
| GRAMD1B | GRAMD1C | ENSP00000402457 | ENSP00000350881 | GRAM domain containing 1B | GRAM domain containing 1C | 0.686 |
| GRAMD1B | GRAMD3 | ENSP00000402457 | ENSP00000426120 | GRAM domain containing 1B | GRAM domain-containing protein 2B; GRAM domain containing 3 | 0.690 |
| GRAMD1B | TMX1 | ENSP00000402457 | ENSP00000393316 | GRAM domain containing 1B | Thioredoxin-related transmembrane protein 1; May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions; Protein disulfide isomerases | 0.522 |
| GRAMD1C | ATP6V1A | ENSP00000350881 | ENSP00000273398 | GRAM domain containing 1C | V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation; Belongs to the ATPase alpha/beta chains family | 0.541 |
| GRAMD1C | CD151 | ENSP00000350881 | ENSP00000380565 | GRAM domain containing 1C | CD151 antigen; Essential for the proper assembly of the glomerular and tubular basement membranes in kidney; Blood group antigens | 0.671 |
| GRAMD1C | GRAMD1B | ENSP00000350881 | ENSP00000402457 | GRAM domain containing 1C | GRAM domain containing 1B | 0.686 |
| GRAMD1C | GRAMD3 | ENSP00000350881 | ENSP00000426120 | GRAM domain containing 1C | GRAM domain-containing protein 2B; GRAM domain containing 3 | 0.783 |
| GRAMD1C | GTPBP8 | ENSP00000350881 | ENSP00000373176 | GRAM domain containing 1C | GTP binding protein 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngB GTPase family | 0.831 |
| GRAMD1C | NAA50 | ENSP00000350881 | ENSP00000240922 | GRAM domain containing 1C | N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity- able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear- able to acetylate H4 in vitro, but this result has not been confirmed in vivo. [...] | 0.717 |
| GRAMD1C | SPICE1 | ENSP00000350881 | ENSP00000295872 | GRAM domain containing 1C | Spindle and centriole-associated protein 1; Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis | 0.667 |
| GRAMD1C | TMEM211 | ENSP00000350881 | ENSP00000385494 | GRAM domain containing 1C | Transmembrane protein 211 | 0.479 |
| GRAMD1C | TMX1 | ENSP00000350881 | ENSP00000393316 | GRAM domain containing 1C | Thioredoxin-related transmembrane protein 1; May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions; Protein disulfide isomerases | 0.671 |
| GRAMD1C | ZNF880 | ENSP00000350881 | ENSP00000406318 | GRAM domain containing 1C | Zinc finger protein 880; Zinc fingers C2H2-type | 0.635 |
| GRAMD3 | GRAMD1B | ENSP00000426120 | ENSP00000402457 | GRAM domain-containing protein 2B; GRAM domain containing 3 | GRAM domain containing 1B | 0.690 |
| GRAMD3 | GRAMD1C | ENSP00000426120 | ENSP00000350881 | GRAM domain-containing protein 2B; GRAM domain containing 3 | GRAM domain containing 1C | 0.783 |
| GTPBP8 | ATP6V1A | ENSP00000373176 | ENSP00000273398 | GTP binding protein 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngB GTPase family | V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation; Belongs to the ATPase alpha/beta chains family | 0.560 |
