• Version:
  • 11.0 [archived version]
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SETD4 SETD4 NDUFAF5 NDUFAF5 ASMTL ASMTL METTL10 METTL10 DBR1 DBR1 RRNAD1 RRNAD1 RSAD1 RSAD1 METTL9 METTL9 MTRF1L MTRF1L COMTD1 COMTD1 IGSF6 IGSF6
"METTL9" - Methyltransferase-like protein 9 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METTL9Methyltransferase-like protein 9; Methyltransferase like 9 (318 aa)    
Predicted Functional Partners:
IGSF6
Immunoglobulin superfamily member 6; V-set domain containing (241 aa)
           
  0.931
RRNAD1
Protein RRNAD1; Ribosomal RNA adenine dimethylase domain containing 1; Belongs to the RRNAD1 family (475 aa)
     
   
  0.697
RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial; May be involved in porphyrin cofactor biosynthesis; Belongs to the anaerobic coproporphyrinogen-III oxidase family (442 aa)
           
  0.671
COMTD1
Catechol O-methyltransferase domain-containing protein 1; Putative O-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family (262 aa)
           
  0.646
METTL10
EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ (291 aa)
           
  0.613
ASMTL
N-acetylserotonin O-methyltransferase-like protein; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity; In the N-terminal section; belongs to the maf family (621 aa)
           
  0.605
SETD4
SET domain containing 4 (440 aa)
     
   
  0.603
DBR1
Lariat debranching enzyme; Cleaves the 2’-5’ phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis; Belongs to the lariat debranching enzyme family (544 aa)
 
 
        0.589
NDUFAF5
Arginine-hydroxylase NDUFAF5, mitochondrial; Arginine hydroxylase involved in the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. Acts by mediating hydroxylation of ’Arg-111’ of NDUFS7. May also have methyltransferase activity (Probable) (345 aa)
           
  0.587
MTRF1L
Peptide chain release factor 1-like, mitochondrial; Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG (380 aa)
     
   
  0.574
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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