STRN3 protein (human) - STRING database

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STRN3

Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Protein phosphatase 2 regulatory subunits (797 aa)

Predicted Functional Partners:

STRIP2

0.965

STRIP1

0.963

MOB4

0.960

SLMAP

0.958

MST4

0.942

CTTNBP2NL

0.942

STK24

0.937

PPP2CB

0.931

PPP2R1A

0.928

PPP2CA

0.926

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTTNBP2NL	MOB4	ENSP00000271277	ENSP00000315702	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	0.952
CTTNBP2NL	MST4	ENSP00000271277	ENSP00000377867	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Serine/threonine-protein kinase 26; Mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily	0.929
CTTNBP2NL	PPP2CA	ENSP00000271277	ENSP00000418447	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at ’Ser-259’; Belongs to the PPP phosphatase family. PP-1 subfamily	0.860
CTTNBP2NL	PPP2CB	ENSP00000271277	ENSP00000221138	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase; Protein phosphatase catalytic subunits	0.882
CTTNBP2NL	PPP2R1A	ENSP00000271277	ENSP00000324804	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT. Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis	0.890
CTTNBP2NL	SLMAP	ENSP00000271277	ENSP00000295951	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Sarcolemmal membrane-associated protein; May play a role during myoblast fusion; STRIPAK complex	0.718
CTTNBP2NL	STK24	ENSP00000271277	ENSP00000365730	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Serine/threonine-protein kinase 24; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress- induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase- independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on ’Thr-442’ and sti [...]	0.908
CTTNBP2NL	STRIP1	ENSP00000271277	ENSP00000358810	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Striatin-interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape; STRIPAK complex	0.960
CTTNBP2NL	STRIP2	ENSP00000271277	ENSP00000249344	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Striatin-interacting protein 2; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Belongs to the STRIP family	0.958
CTTNBP2NL	STRN3	ENSP00000271277	ENSP00000350071	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Protein phosphatase 2 regulatory subunits	0.942
MOB4	CTTNBP2NL	ENSP00000315702	ENSP00000271277	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	0.952
MOB4	MST4	ENSP00000315702	ENSP00000377867	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Serine/threonine-protein kinase 26; Mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily	0.952
MOB4	PPP2CA	ENSP00000315702	ENSP00000418447	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at ’Ser-259’; Belongs to the PPP phosphatase family. PP-1 subfamily	0.937
MOB4	PPP2CB	ENSP00000315702	ENSP00000221138	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase; Protein phosphatase catalytic subunits	0.891
MOB4	PPP2R1A	ENSP00000315702	ENSP00000324804	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT. Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis	0.937
MOB4	SLMAP	ENSP00000315702	ENSP00000295951	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Sarcolemmal membrane-associated protein; May play a role during myoblast fusion; STRIPAK complex	0.953
MOB4	STK24	ENSP00000315702	ENSP00000365730	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Serine/threonine-protein kinase 24; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress- induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase- independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on ’Thr-442’ and sti [...]	0.944
MOB4	STRIP1	ENSP00000315702	ENSP00000358810	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Striatin-interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape; STRIPAK complex	0.970
MOB4	STRIP2	ENSP00000315702	ENSP00000249344	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Striatin-interacting protein 2; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Belongs to the STRIP family	0.962
MOB4	STRN3	ENSP00000315702	ENSP00000350071	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Protein phosphatase 2 regulatory subunits	0.960

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