PEX2 protein (human) - STRING database

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Score

PEX2

Peroxisome biogenesis factor 2; Somewhat implicated in the biogenesis of peroxisomes; Belongs to the pex2/pex10/pex12 family (305 aa)

Predicted Functional Partners:

PEX10

0.999

PEX12

0.998

PEX13

0.996

PEX7

0.995

PEX6

0.993

PEX14

0.991

PEX1

0.988

PEX26

0.975

GNPAT

0.971

PEX5

0.962

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNPAT	PEX1	ENSP00000355607	ENSP00000248633	Glyceronephosphate O-acyltransferase	Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	0.734
GNPAT	PEX10	ENSP00000355607	ENSP00000288774	Glyceronephosphate O-acyltransferase	Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes; Peroxins	0.963
GNPAT	PEX12	ENSP00000355607	ENSP00000482609	Glyceronephosphate O-acyltransferase	Peroxisome assembly protein 12; Required for protein import into peroxisomes; Peroxins	0.962
GNPAT	PEX13	ENSP00000355607	ENSP00000295030	Glyceronephosphate O-acyltransferase	Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins; Peroxins	0.963
GNPAT	PEX14	ENSP00000355607	ENSP00000349016	Glyceronephosphate O-acyltransferase	Peroxisomal membrane protein PEX14; Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin; Peroxins	0.967
GNPAT	PEX2	ENSP00000355607	ENSP00000349543	Glyceronephosphate O-acyltransferase	Peroxisome biogenesis factor 2; Somewhat implicated in the biogenesis of peroxisomes; Belongs to the pex2/pex10/pex12 family	0.971
GNPAT	PEX26	ENSP00000355607	ENSP00000331106	Glyceronephosphate O-acyltransferase	Peroxisome assembly protein 26; Probably required for protein import into peroxisomes. Anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Involved in the import of catalase and proteins containing a PTS2 target sequence, but not in import of proteins with a PTS1 target sequence; Peroxins	0.740
GNPAT	PEX5	ENSP00000355607	ENSP00000391601	Glyceronephosphate O-acyltransferase	Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import	0.715
GNPAT	PEX6	ENSP00000355607	ENSP00000303511	Glyceronephosphate O-acyltransferase	Peroxisome assembly factor 2; Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	0.655
GNPAT	PEX7	ENSP00000355607	ENSP00000315680	Glyceronephosphate O-acyltransferase	Peroxisomal targeting signal 2 receptor; Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import; Belongs to the WD repeat peroxin-7 family	0.756
PEX1	GNPAT	ENSP00000248633	ENSP00000355607	Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	Glyceronephosphate O-acyltransferase	0.734
PEX1	PEX10	ENSP00000248633	ENSP00000288774	Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes; Peroxins	0.991
PEX1	PEX12	ENSP00000248633	ENSP00000482609	Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	Peroxisome assembly protein 12; Required for protein import into peroxisomes; Peroxins	0.993
PEX1	PEX13	ENSP00000248633	ENSP00000295030	Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins; Peroxins	0.993
PEX1	PEX14	ENSP00000248633	ENSP00000349016	Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	Peroxisomal membrane protein PEX14; Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin; Peroxins	0.985
PEX1	PEX2	ENSP00000248633	ENSP00000349543	Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	Peroxisome biogenesis factor 2; Somewhat implicated in the biogenesis of peroxisomes; Belongs to the pex2/pex10/pex12 family	0.988
PEX1	PEX26	ENSP00000248633	ENSP00000331106	Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	Peroxisome assembly protein 26; Probably required for protein import into peroxisomes. Anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Involved in the import of catalase and proteins containing a PTS2 target sequence, but not in import of proteins with a PTS1 target sequence; Peroxins	0.988
PEX1	PEX5	ENSP00000248633	ENSP00000391601	Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import	0.920
PEX1	PEX6	ENSP00000248633	ENSP00000303511	Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	Peroxisome assembly factor 2; Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	0.982
PEX1	PEX7	ENSP00000248633	ENSP00000315680	Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes	Peroxisomal targeting signal 2 receptor; Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import; Belongs to the WD repeat peroxin-7 family	0.987

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