• Version:
  • 11.0 [archived version]
STRINGSTRING
KIAA1143 KIAA1143 OR13C8 OR13C8 JAKMIP2 JAKMIP2 POF1B POF1B ZNF790 ZNF790 EPHB2 EPHB2 TRIM28 TRIM28 DIP2C DIP2C
"ZNF790" - Zinc finger protein 790 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF790Zinc finger protein 790; May be involved in transcriptional regulation; Zinc fingers C2H2-type (636 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.918
OR13C8
Olfactory receptor 13C8; Odorant receptor; Olfactory receptors, family 13 (320 aa)
           
  0.571
KIAA1143
Uncharacterized protein KIAA1143; KIAA1143 (154 aa)
           
  0.570
JAKMIP2
Janus kinase and microtubule interacting protein 2; Belongs to the JAKMIP family (820 aa)
           
  0.478
DIP2C
Disco interacting protein 2 homolog C (1556 aa)
     
   
  0.430
EPHB2
Ephrin type-B receptor 2; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral corte [...] (987 aa)
     
 
  0.428
POF1B
Protein POF1B; Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development (589 aa)
           
  0.424
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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