AADACL2 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AADACL2

Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family (401 aa)

Predicted Functional Partners:

SUCNR1

0.734

AASDH

0.559

AAED1

0.537

AAGAB

0.511

A4GNT

0.510

AAMDC

0.479

AARSD1

0.475

AASS

0.458

AARD

0.450

AAR2

0.440

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A4GNT	AADACL2	ENSP00000236709	ENSP00000348911	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity); Alpha 1,4-glycosyltransferases	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	0.510
A4GNT	AAED1	ENSP00000236709	ENSP00000364382	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity); Alpha 1,4-glycosyltransferases	Thioredoxin-like protein AAED1; AhpC/TSA antioxidant enzyme domain containing 1; Belongs to the AAED1 family	0.508
A4GNT	AAGAB	ENSP00000236709	ENSP00000261880	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity); Alpha 1,4-glycosyltransferases	Alpha- and gamma-adaptin-binding protein p34; May be involved in endocytic recycling of growth factor receptors such as EGFR	0.473
A4GNT	AAMDC	ENSP00000236709	ENSP00000431808	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity); Alpha 1,4-glycosyltransferases	Mth938 domain-containing protein; May play a role in preadipocyte differentiation and adipogenesis; Belongs to the AAMDC family	0.446
A4GNT	AAR2	ENSP00000236709	ENSP00000363043	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity); Alpha 1,4-glycosyltransferases	Protein AAR2 homolog; Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing	0.400
A4GNT	AARD	ENSP00000236709	ENSP00000367528	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity); Alpha 1,4-glycosyltransferases	Alanine and arginine rich domain containing protein	0.420
A4GNT	AARSD1	ENSP00000236709	ENSP00000400870	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity); Alpha 1,4-glycosyltransferases	Alanyl-tRNA editing protein Aarsd1; Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala)	0.442
A4GNT	AASS	ENSP00000236709	ENSP00000377040	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity); Alpha 1,4-glycosyltransferases	Alpha-aminoadipic semialdehyde synthase, mitochondrial; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively	0.426
AADACL2	A4GNT	ENSP00000348911	ENSP00000236709	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity); Alpha 1,4-glycosyltransferases	0.510
AADACL2	AAED1	ENSP00000348911	ENSP00000364382	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	Thioredoxin-like protein AAED1; AhpC/TSA antioxidant enzyme domain containing 1; Belongs to the AAED1 family	0.537
AADACL2	AAGAB	ENSP00000348911	ENSP00000261880	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	Alpha- and gamma-adaptin-binding protein p34; May be involved in endocytic recycling of growth factor receptors such as EGFR	0.511
AADACL2	AAMDC	ENSP00000348911	ENSP00000431808	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	Mth938 domain-containing protein; May play a role in preadipocyte differentiation and adipogenesis; Belongs to the AAMDC family	0.479
AADACL2	AAR2	ENSP00000348911	ENSP00000363043	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	Protein AAR2 homolog; Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing	0.440
AADACL2	AARD	ENSP00000348911	ENSP00000367528	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	Alanine and arginine rich domain containing protein	0.450
AADACL2	AARSD1	ENSP00000348911	ENSP00000400870	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	Alanyl-tRNA editing protein Aarsd1; Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala)	0.475
AADACL2	AASDH	ENSP00000348911	ENSP00000205214	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	Acyl-CoA synthetase family member 4; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA; Acyl-CoA synthetase family	0.559
AADACL2	AASS	ENSP00000348911	ENSP00000377040	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	Alpha-aminoadipic semialdehyde synthase, mitochondrial; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively	0.458
AADACL2	SUCNR1	ENSP00000348911	ENSP00000355156	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	Succinate receptor 1; Receptor for succinate	0.734
AAED1	A4GNT	ENSP00000364382	ENSP00000236709	Thioredoxin-like protein AAED1; AhpC/TSA antioxidant enzyme domain containing 1; Belongs to the AAED1 family	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity); Alpha 1,4-glycosyltransferases	0.508
AAED1	AADACL2	ENSP00000364382	ENSP00000348911	Thioredoxin-like protein AAED1; AhpC/TSA antioxidant enzyme domain containing 1; Belongs to the AAED1 family	Arylacetamide deacetylase-like 2; Arylacetamide deacetylase family; Belongs to the ’GDXG’ lipolytic enzyme family	0.537

page 1 of 4

Network

Neighborhood

Textmining

Cooccurrence

Experiments

Coexpression

Databases

Fusion

© STRING Consortium 2020

Credits

Access

Info

About