| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BPIFA3 | BPIFB6 | ENSP00000364603 | ENSP00000344929 | BPI fold containing family A member 3; Belongs to the BPI/LBP/Plunc superfamily. Plunc family | BPI fold containing family B member 6; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family | 0.802 |
| BPIFA3 | SUN5 | ENSP00000364603 | ENSP00000348496 | BPI fold containing family A member 3; Belongs to the BPI/LBP/Plunc superfamily. Plunc family | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | 0.585 |
| BPIFB6 | BPIFA3 | ENSP00000344929 | ENSP00000364603 | BPI fold containing family B member 6; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family | BPI fold containing family A member 3; Belongs to the BPI/LBP/Plunc superfamily. Plunc family | 0.802 |
| BPIFB6 | SUN5 | ENSP00000344929 | ENSP00000348496 | BPI fold containing family B member 6; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | 0.581 |
| CCDC155 | DPY19L2 | ENSP00000404220 | ENSP00000315988 | Protein KASH5; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for telomere attachment to nuclear envelope in the prophase of meiosis and for rapid telomere prophase movements implicating a SUN1/2-KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redunda [...] | Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family | 0.494 |
| CCDC155 | SUN5 | ENSP00000404220 | ENSP00000348496 | Protein KASH5; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for telomere attachment to nuclear envelope in the prophase of meiosis and for rapid telomere prophase movements implicating a SUN1/2-KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redunda [...] | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | 0.665 |
| CCDC155 | SYNE3 | ENSP00000404220 | ENSP00000334308 | Protein KASH5; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for telomere attachment to nuclear envelope in the prophase of meiosis and for rapid telomere prophase movements implicating a SUN1/2-KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redunda [...] | Nesprin-3; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is re [...] | 0.815 |
| CCDC155 | SYNE4 | ENSP00000404220 | ENSP00000316130 | Protein KASH5; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for telomere attachment to nuclear envelope in the prophase of meiosis and for rapid telomere prophase movements implicating a SUN1/2-KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redunda [...] | Nesprin-4; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning (By similarity). Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependen [...] | 0.878 |
| DPY19L2 | CCDC155 | ENSP00000315988 | ENSP00000404220 | Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family | Protein KASH5; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for telomere attachment to nuclear envelope in the prophase of meiosis and for rapid telomere prophase movements implicating a SUN1/2-KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redunda [...] | 0.494 |
| DPY19L2 | SUN5 | ENSP00000315988 | ENSP00000348496 | Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | 0.763 |
| GPATCH4 | SUN5 | ENSP00000396441 | ENSP00000348496 | G-patch domain containing 4 | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | 0.571 |
| ODF1 | SUN5 | ENSP00000285402 | ENSP00000348496 | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail; Small heat shock proteins | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | 0.640 |
| RFT1 | SUN5 | ENSP00000296292 | ENSP00000348496 | Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | 0.585 |
| RTF1 | SUN5 | ENSP00000374280 | ENSP00000348496 | RNA polymerase-associated protein RTF1 homolog; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non- phosphorylated and ’Ser-2’- and ’Ser-5’-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription [...] | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | 0.585 |
| SUN5 | BPIFA3 | ENSP00000348496 | ENSP00000364603 | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | BPI fold containing family A member 3; Belongs to the BPI/LBP/Plunc superfamily. Plunc family | 0.585 |
| SUN5 | BPIFB6 | ENSP00000348496 | ENSP00000344929 | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | BPI fold containing family B member 6; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family | 0.581 |
| SUN5 | CCDC155 | ENSP00000348496 | ENSP00000404220 | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | Protein KASH5; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for telomere attachment to nuclear envelope in the prophase of meiosis and for rapid telomere prophase movements implicating a SUN1/2-KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redunda [...] | 0.665 |
| SUN5 | DPY19L2 | ENSP00000348496 | ENSP00000315988 | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family | 0.763 |
| SUN5 | GPATCH4 | ENSP00000348496 | ENSP00000396441 | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | G-patch domain containing 4 | 0.571 |
| SUN5 | ODF1 | ENSP00000348496 | ENSP00000285402 | SUN domain-containing protein 5; May be involved in meiotic stage of spermatogenesis | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail; Small heat shock proteins | 0.640 |
