• Version:
  • 11.0 [archived version]
STRINGSTRING
C8orf44 C8orf44 OPA3 OPA3 C17orf75 C17orf75 GK5 GK5 ICA1L ICA1L DCAF10 DCAF10 CYP20A1 CYP20A1 SYNJ2BP SYNJ2BP FKBP14 FKBP14 ABI2 ABI2 CYP27C1 CYP27C1
"CYP20A1" - Cytochrome P450 family 20 subfamily A member 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP20A1Cytochrome P450 family 20 subfamily A member 1 (462 aa)    
Predicted Functional Partners:
ICA1L
Islet cell autoantigen 1-like protein; Classical BAR domain containing (482 aa)
       
 
  0.763
C8orf44
Putative uncharacterized protein C8orf44; Chromosome 8 open reading frame 44 (159 aa)
           
  0.725
DCAF10
DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors (559 aa)
           
  0.697
C17orf75
Protein Njmu-R1; May have a role in spermatogenesis (396 aa)
           
  0.694
CYP27C1
Cytochrome P450 27C1; Catalyzes the conversion of all-trans retinol (also called vitamin A1, the precursor of 11-cis retinal) to 3,4- didehydroretinol (also called vitamin A2, the precursor of 11-cis 3,4-didehydroretinal). Also acts on all-trans retinal and all- trans retinoic acid; Cytochrome P450 family 27 (372 aa)
   
   
  0.679
GK5
Glycerol kinase 5 (529 aa)
           
  0.657
SYNJ2BP
Synaptojanin-2-binding protein; Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction; PDZ domain containing (145 aa)
           
  0.656
ABI2
Abl interactor 2; May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity) (513 aa)
     
   
  0.653
FKBP14
Peptidyl-prolyl cis-trans isomerase FKBP14; PPIases accelerate the folding of proteins during protein synthesis; EF-hand domain containing (211 aa)
       
 
  0.646
OPA3
Optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia); OPA3, outer mitochondrial membrane lipid metabolism regulator (180 aa)
           
  0.644
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]