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  • 11.0 [archived version]
STRINGSTRING
KIFC3 KIFC3 MAP3K7CL MAP3K7CL SIPA1 SIPA1 PPP1R35 PPP1R35 MPHOSPH9 MPHOSPH9 PCNXL3 PCNXL3 DNAJC5G DNAJC5G CFAP69 CFAP69 STARD9 STARD9 TNFAIP1 TNFAIP1 WDR70 WDR70
"PCNXL3" - Pecanex-like 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCNXL3Pecanex-like 3 (Drosophila); Belongs to the pecanex family (2034 aa)    
Predicted Functional Partners:
STARD9
StAR-related lipid transfer protein 9; Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM); Kinesins (4700 aa)
     
   
  0.642
MPHOSPH9
M-phase phosphoprotein 9 (1183 aa)
           
  0.586
SIPA1
Signal-induced proliferation-associated protein 1; GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state. Affects cell cycle progression (By similarity); PDZ domain containing (1042 aa)
 
 
   
  0.569
PPP1R35
Protein phosphatase 1 regulatory subunit 35; Inhibits PPP1CA phosphatase activity; Protein phosphatase 1 regulatory subunits (253 aa)
     
   
  0.530
CFAP69
Cilia- and flagella-associated protein 69; Armadillo-like helical domain containing (941 aa)
           
  0.520
DNAJC5G
DnaJ heat shock protein family member C5 gamma (189 aa)
           
  0.495
MAP3K7CL
MAP3K7 C-terminal-like protein; MAP3K7 C-terminal like (242 aa)
           
  0.491
TNFAIP1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity; Belongs to the BACURD family (316 aa)
           
  0.482
WDR70
WD repeat-containing protein 70; WD repeat domain containing; Belongs to the WD repeat GAD-1 family (654 aa)
           
  0.474
KIFC3
Kinesin-like protein KIFC3; Minus-end microtubule-dependent motor protein. Involved in apically targeted transport (By similarity). Required for zonula adherens maintenance; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family (833 aa)
           
  0.463
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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