• Version:
  • 11.0 [archived version]
STRINGSTRING
FZR1 FZR1 MFSD12 MFSD12 MFSD8 MFSD8 MFSD6 MFSD6 MFSD11 MFSD11 KIAA1919 KIAA1919 MFSD10 MFSD10 TMEM180 TMEM180 MFSD9 MFSD9 MFSD6L MFSD6L MFSD3 MFSD3
"MFSD12" - Major facilitator superfamily domain containing 12 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
MFSD12Major facilitator superfamily domain containing 12 (480 aa)    
Predicted Functional Partners:
FZR1
Fizzy-related protein homolog; Substrate-specific adapter for the anaphase promoting complex/cyclosome (APC/C) E3 ubiquitin-protein ligase complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint- its dephosphorylation and [...] (496 aa)
     
   
  0.907
MFSD9
Major facilitator superfamily domain containing 9 (474 aa)
           
  0.773
TMEM180
Transmembrane protein 180 (517 aa)
           
  0.771
MFSD6L
Major facilitator superfamily domain containing 6 like (586 aa)
     
   
  0.769
MFSD11
UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family (449 aa)
           
  0.727
MFSD3
Major facilitator superfamily domain containing 3 (412 aa)
   
   
  0.719
MFSD6
Major facilitator superfamily domain containing 6 (791 aa)
     
   
  0.700
MFSD8
Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily (518 aa)
           
  0.681
MFSD10
Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump (455 aa)
     
   
  0.680
KIAA1919
Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney (518 aa)
           
  0.677
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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