node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FZR1 | MFSD12 | ENSP00000378529 | ENSP00000347583 | Fizzy-related protein homolog; Substrate-specific adapter for the anaphase promoting complex/cyclosome (APC/C) E3 ubiquitin-protein ligase complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint- its dephosphorylation and [...] | Major facilitator superfamily domain containing 12 | 0.907 |
KIAA1919 | MFSD10 | ENSP00000357840 | ENSP00000332646 | Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | 0.774 |
KIAA1919 | MFSD11 | ENSP00000357840 | ENSP00000464932 | Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family | 0.780 |
KIAA1919 | MFSD12 | ENSP00000357840 | ENSP00000347583 | Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney | Major facilitator superfamily domain containing 12 | 0.677 |
KIAA1919 | MFSD3 | ENSP00000357840 | ENSP00000301327 | Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney | Major facilitator superfamily domain containing 3 | 0.563 |
KIAA1919 | MFSD6 | ENSP00000357840 | ENSP00000376141 | Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney | Major facilitator superfamily domain containing 6 | 0.571 |
KIAA1919 | MFSD6L | ENSP00000357840 | ENSP00000330051 | Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney | Major facilitator superfamily domain containing 6 like | 0.656 |
KIAA1919 | MFSD8 | ENSP00000357840 | ENSP00000296468 | Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney | Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily | 0.720 |
KIAA1919 | MFSD9 | ENSP00000357840 | ENSP00000258436 | Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney | Major facilitator superfamily domain containing 9 | 0.706 |
KIAA1919 | TMEM180 | ENSP00000357840 | ENSP00000238936 | Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney | Transmembrane protein 180 | 0.669 |
MFSD10 | KIAA1919 | ENSP00000332646 | ENSP00000357840 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney | 0.774 |
MFSD10 | MFSD11 | ENSP00000332646 | ENSP00000464932 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family | 0.770 |
MFSD10 | MFSD12 | ENSP00000332646 | ENSP00000347583 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Major facilitator superfamily domain containing 12 | 0.680 |
MFSD10 | MFSD3 | ENSP00000332646 | ENSP00000301327 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Major facilitator superfamily domain containing 3 | 0.536 |
MFSD10 | MFSD6 | ENSP00000332646 | ENSP00000376141 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Major facilitator superfamily domain containing 6 | 0.523 |
MFSD10 | MFSD6L | ENSP00000332646 | ENSP00000330051 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Major facilitator superfamily domain containing 6 like | 0.562 |
MFSD10 | MFSD8 | ENSP00000332646 | ENSP00000296468 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily | 0.737 |
MFSD10 | TMEM180 | ENSP00000332646 | ENSP00000238936 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Transmembrane protein 180 | 0.583 |
MFSD11 | KIAA1919 | ENSP00000464932 | ENSP00000357840 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family | Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney | 0.780 |
MFSD11 | MFSD10 | ENSP00000464932 | ENSP00000332646 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | 0.770 |