• Version:
  • 11.0 [archived version]
STRINGSTRING
FAM71B FAM71B FAM71E1 FAM71E1 MORN5 MORN5 ORAI1 ORAI1 MORN2 MORN2 MORN3 MORN3 TMEM120B TMEM120B RHOF RHOF SETD1B SETD1B SPEM1 SPEM1 MEIG1 MEIG1
"MORN3" - MORN repeat containing 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MORN3MORN repeat containing 3 (240 aa)    
Predicted Functional Partners:
MORN5
MORN repeat containing 5 (161 aa)
    
   
  0.835
TMEM120B
Transmembrane protein 120B; Necessary for efficient adipogenesis; Belongs to the TMEM120 family (339 aa)
            
  0.819
MORN2
MORN repeat-containing protein 2; Might have a role in spermatogenesis (79 aa)
    
   
  0.717
RHOF
Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology; Rho family GTPases (211 aa)
            
  0.693
MEIG1
Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis (88 aa)
      
   
  0.633
SETD1B
Histone-lysine N-methyltransferase SETD1B; Histone methyltransferase that specifically methylates ’Lys-4’ of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring ’Lys- 9’ residue is already methylated. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. The non-overlapping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates ’Lys-4’ of histone H3 in vitro; Belongs t [...] (1923 aa)
      
   
  0.576
FAM71B
Protein FAM71B; May be involved in RNA biogenesis (605 aa)
            
  0.557
ORAI1
Calcium release-activated calcium channel protein 1; Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT; Belongs to the Orai family (301 aa)
            
  0.540
FAM71E1
Protein FAM71E1; Family with sequence similarity 71 member E1 (231 aa)
            
  0.538
SPEM1
Spermatid maturation protein 1; Required for proper cytoplasm removal during spermatogenesis (309 aa)
            
  0.528
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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