• Version:
  • 11.0 [archived version]
STRINGSTRING
MRPL3 MRPL3 MRPL41 MRPL41 MRPL38 MRPL38 MRPL40 MRPL40 MRPL52 MRPL52 MRPS30 MRPS30 MRPL51 MRPL51 MRPL32 MRPL32 MRPL13 MRPL13 ICT1 ICT1 MRPL49 MRPL49
"MRPL52" - Mitochondrial ribosomal protein L52 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRPL52Mitochondrial ribosomal protein L52 (123 aa)    
Predicted Functional Partners:
MRPL41
39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (137 aa)
     
  0.998
MRPL38
Mitochondrial ribosomal protein L38; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily (380 aa)
     
  0.998
MRPL13
Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family (178 aa)
     
  0.997
MRPL51
Mitochondrial ribosomal protein L51; Belongs to the mitochondrion-specific ribosomal protein mL51 family (128 aa)
     
  0.997
ICT1
Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (206 aa)
     
  0.997
MRPL32
Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family (188 aa)
     
    0.996
MRPL3
Mitochondrial ribosomal protein L3 (348 aa)
     
    0.996
MRPL40
Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family (206 aa)
     
  0.996
MRPL49
Mitochondrial ribosomal protein L49 (166 aa)
     
    0.996
MRPS30
Mitochondrial ribosomal protein S30 (439 aa)
     
  0.995
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]