node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BICD1 | CCDC17 | ENSP00000281474 | ENSP00000432172 | Protein bicaudal D homolog 1; Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex; Belongs to the BicD family | Coiled-coil domain containing 17 | 0.532 |
BICD1 | GPBP1L1 | ENSP00000281474 | ENSP00000347224 | Protein bicaudal D homolog 1; Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex; Belongs to the BicD family | Vasculin-like protein 1; Possible transcription factor | 0.566 |
BICD1 | LRRC7 | ENSP00000281474 | ENSP00000035383 | Protein bicaudal D homolog 1; Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex; Belongs to the BicD family | Leucine-rich repeat-containing protein 7; Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression; Belongs to the LAP (LRR and PDZ) protein family | 0.554 |
BICD1 | TMEM69 | ENSP00000281474 | ENSP00000361095 | Protein bicaudal D homolog 1; Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex; Belongs to the BicD family | Transmembrane protein 69 | 0.563 |
CCDC17 | BICD1 | ENSP00000432172 | ENSP00000281474 | Coiled-coil domain containing 17 | Protein bicaudal D homolog 1; Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex; Belongs to the BicD family | 0.532 |
CCDC17 | GPBP1L1 | ENSP00000432172 | ENSP00000347224 | Coiled-coil domain containing 17 | Vasculin-like protein 1; Possible transcription factor | 0.864 |
CCDC17 | LRRC7 | ENSP00000432172 | ENSP00000035383 | Coiled-coil domain containing 17 | Leucine-rich repeat-containing protein 7; Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression; Belongs to the LAP (LRR and PDZ) protein family | 0.774 |
CCDC17 | TMEM69 | ENSP00000432172 | ENSP00000361095 | Coiled-coil domain containing 17 | Transmembrane protein 69 | 0.831 |
EIF3A | GPBP1L1 | ENSP00000358140 | ENSP00000347224 | Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] | Vasculin-like protein 1; Possible transcription factor | 0.544 |
GPBP1L1 | BICD1 | ENSP00000347224 | ENSP00000281474 | Vasculin-like protein 1; Possible transcription factor | Protein bicaudal D homolog 1; Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex; Belongs to the BicD family | 0.566 |
GPBP1L1 | CCDC17 | ENSP00000347224 | ENSP00000432172 | Vasculin-like protein 1; Possible transcription factor | Coiled-coil domain containing 17 | 0.864 |
GPBP1L1 | EIF3A | ENSP00000347224 | ENSP00000358140 | Vasculin-like protein 1; Possible transcription factor | Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] | 0.544 |
GPBP1L1 | GPC5 | ENSP00000347224 | ENSP00000366267 | Vasculin-like protein 1; Possible transcription factor | Glypican-5; Cell surface proteoglycan that bears heparan sulfate; Belongs to the glypican family | 0.598 |
GPBP1L1 | LRRC7 | ENSP00000347224 | ENSP00000035383 | Vasculin-like protein 1; Possible transcription factor | Leucine-rich repeat-containing protein 7; Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression; Belongs to the LAP (LRR and PDZ) protein family | 0.774 |
GPBP1L1 | NANOS2 | ENSP00000347224 | ENSP00000341021 | Vasculin-like protein 1; Possible transcription factor | Nanos homolog 2; Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for t [...] | 0.555 |
GPBP1L1 | RANBP10 | ENSP00000347224 | ENSP00000316589 | Vasculin-like protein 1; Possible transcription factor | Ran-binding protein 10; Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase (By similarity). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function (By similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen- induced transactivation. In contrast to RANBP9, does not interact with Sos [...] | 0.772 |
GPBP1L1 | TMEM69 | ENSP00000347224 | ENSP00000361095 | Vasculin-like protein 1; Possible transcription factor | Transmembrane protein 69 | 0.849 |
GPBP1L1 | ZFYVE27 | ENSP00000347224 | ENSP00000377282 | Vasculin-like protein 1; Possible transcription factor | Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity (By similarity). Involved in nerve growth factor-induced neurite formation in VAPA- dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections. Acts as an adapter protein and facilitates the interaction of KIF5A [...] | 0.619 |
GPBP1L1 | ZNF700 | ENSP00000347224 | ENSP00000479449 | Vasculin-like protein 1; Possible transcription factor | Zinc finger protein 700; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.668 |
GPC5 | GPBP1L1 | ENSP00000366267 | ENSP00000347224 | Glypican-5; Cell surface proteoglycan that bears heparan sulfate; Belongs to the glypican family | Vasculin-like protein 1; Possible transcription factor | 0.598 |