node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC159 | KANK2 | ENSP00000468232 | ENSP00000468002 | Coiled-coil domain containing 159 | KN motif and ankyrin repeat domain-containing protein 2; Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIF [...] | 0.566 |
CCDC159 | LPPR2 | ENSP00000468232 | ENSP00000466898 | Coiled-coil domain containing 159 | Lipid phosphate phosphatase-related protein type 2 | 0.725 |
CCDC159 | RAB3D | ENSP00000468232 | ENSP00000222120 | Coiled-coil domain containing 159 | Ras-related protein Rab-3D; Protein transport. Probably involved in regulated exocytosis (By similarity); Belongs to the small GTPase superfamily. Rab family | 0.440 |
CCDC159 | SWSAP1 | ENSP00000468232 | ENSP00000310008 | Coiled-coil domain containing 159 | ATPase SWSAP1; ATPase which is preferentially stimulated by single- stranded DNA and is involved in homologous recombination repair (HRR). Has a DNA-binding activity which is independent of its ATPase activity; CTLH complex | 0.703 |
CCDC159 | TMEM205 | ENSP00000468232 | ENSP00000346954 | Coiled-coil domain containing 159 | Transmembrane protein 205; In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin | 0.651 |
KANK2 | CCDC159 | ENSP00000468002 | ENSP00000468232 | KN motif and ankyrin repeat domain-containing protein 2; Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIF [...] | Coiled-coil domain containing 159 | 0.566 |
KANK2 | LPPR2 | ENSP00000468002 | ENSP00000466898 | KN motif and ankyrin repeat domain-containing protein 2; Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIF [...] | Lipid phosphate phosphatase-related protein type 2 | 0.477 |
KANK2 | SWSAP1 | ENSP00000468002 | ENSP00000310008 | KN motif and ankyrin repeat domain-containing protein 2; Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIF [...] | ATPase SWSAP1; ATPase which is preferentially stimulated by single- stranded DNA and is involved in homologous recombination repair (HRR). Has a DNA-binding activity which is independent of its ATPase activity; CTLH complex | 0.599 |
KANK2 | TMEM205 | ENSP00000468002 | ENSP00000346954 | KN motif and ankyrin repeat domain-containing protein 2; Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIF [...] | Transmembrane protein 205; In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin | 0.618 |
KLHL29 | LPPR2 | ENSP00000420659 | ENSP00000466898 | Kelch-like protein 29; Kelch like family member 29; BTB domain containing | Lipid phosphate phosphatase-related protein type 2 | 0.411 |
KLHL29 | MOXD1 | ENSP00000420659 | ENSP00000356940 | Kelch-like protein 29; Kelch like family member 29; BTB domain containing | Monooxygenase DBH like 1; Belongs to the copper type II ascorbate-dependent monooxygenase family | 0.690 |
KLHL29 | SWSAP1 | ENSP00000420659 | ENSP00000310008 | Kelch-like protein 29; Kelch like family member 29; BTB domain containing | ATPase SWSAP1; ATPase which is preferentially stimulated by single- stranded DNA and is involved in homologous recombination repair (HRR). Has a DNA-binding activity which is independent of its ATPase activity; CTLH complex | 0.471 |
KLHL29 | TMEM205 | ENSP00000420659 | ENSP00000346954 | Kelch-like protein 29; Kelch like family member 29; BTB domain containing | Transmembrane protein 205; In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin | 0.512 |
LPPR2 | CCDC159 | ENSP00000466898 | ENSP00000468232 | Lipid phosphate phosphatase-related protein type 2 | Coiled-coil domain containing 159 | 0.725 |
LPPR2 | KANK2 | ENSP00000466898 | ENSP00000468002 | Lipid phosphate phosphatase-related protein type 2 | KN motif and ankyrin repeat domain-containing protein 2; Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIF [...] | 0.477 |
LPPR2 | KLHL29 | ENSP00000466898 | ENSP00000420659 | Lipid phosphate phosphatase-related protein type 2 | Kelch-like protein 29; Kelch like family member 29; BTB domain containing | 0.411 |
LPPR2 | SWSAP1 | ENSP00000466898 | ENSP00000310008 | Lipid phosphate phosphatase-related protein type 2 | ATPase SWSAP1; ATPase which is preferentially stimulated by single- stranded DNA and is involved in homologous recombination repair (HRR). Has a DNA-binding activity which is independent of its ATPase activity; CTLH complex | 0.774 |
LPPR2 | TMEM205 | ENSP00000466898 | ENSP00000346954 | Lipid phosphate phosphatase-related protein type 2 | Transmembrane protein 205; In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin | 0.671 |
MOXD1 | KLHL29 | ENSP00000356940 | ENSP00000420659 | Monooxygenase DBH like 1; Belongs to the copper type II ascorbate-dependent monooxygenase family | Kelch-like protein 29; Kelch like family member 29; BTB domain containing | 0.690 |
MOXD1 | SWSAP1 | ENSP00000356940 | ENSP00000310008 | Monooxygenase DBH like 1; Belongs to the copper type II ascorbate-dependent monooxygenase family | ATPase SWSAP1; ATPase which is preferentially stimulated by single- stranded DNA and is involved in homologous recombination repair (HRR). Has a DNA-binding activity which is independent of its ATPase activity; CTLH complex | 0.509 |