• Version:
  • 11.0 [archived version]
STRINGSTRING
LPHN2 LPHN2 R3HCC1L R3HCC1L ENSG00000259030 ENSG00000259030 TNNI3K TNNI3K LPHN3 LPHN3 LRRIQ3 LRRIQ3 FPGT FPGT ZNF33B ZNF33B TMC7 TMC7 SAMD5 SAMD5 LPHN1 LPHN1
"LRRIQ3" - Leucine rich repeats and IQ motif containing 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
LRRIQ3Leucine rich repeats and IQ motif containing 3 (624 aa)    
Predicted Functional Partners:
ENSG00000259030
FPGT-TNNI3K readthrough; Ankyrin repeat domain containing (949 aa)
       
 
  0.819
TNNI3K
Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily (835 aa)
       
 
  0.775
TMC7
Transmembrane channel-like protein 7; Probable ion channel; Transmembrane channel likes (758 aa)
           
  0.770
FPGT
Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids (607 aa)
     
   
  0.752
ZNF33B
Zinc finger protein 33B; May be involved in transcriptional regulation; Zinc fingers C2H2-type (778 aa)
       
 
  0.713
SAMD5
Sterile alpha motif domain containing 5 (173 aa)
           
  0.709
R3HCC1L
Coiled-coil domain-containing protein R3HCC1L; R3H domain and coiled-coil containing 1 like (792 aa)
     
      0.698
LPHN3
Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily (1469 aa)
       
      0.683
LPHN1
Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) (1474 aa)
       
      0.683
LPHN2
Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily (1403 aa)
       
      0.683
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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