node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSG00000259030 | LRRIQ3 | ENSP00000450895 | ENSP00000346414 | FPGT-TNNI3K readthrough; Ankyrin repeat domain containing | Leucine rich repeats and IQ motif containing 3 | 0.819 |
ENSG00000259030 | TNNI3K | ENSP00000450895 | ENSP00000322251 | FPGT-TNNI3K readthrough; Ankyrin repeat domain containing | Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily | 0.806 |
FPGT | LRRIQ3 | ENSP00000359935 | ENSP00000346414 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids | Leucine rich repeats and IQ motif containing 3 | 0.752 |
FPGT | TNNI3K | ENSP00000359935 | ENSP00000322251 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids | Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily | 0.750 |
FPGT | ZNF33B | ENSP00000359935 | ENSP00000352444 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids | Zinc finger protein 33B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.529 |
LPHN1 | LRRIQ3 | ENSP00000340688 | ENSP00000346414 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | Leucine rich repeats and IQ motif containing 3 | 0.683 |
LPHN2 | LRRIQ3 | ENSP00000322270 | ENSP00000346414 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | Leucine rich repeats and IQ motif containing 3 | 0.683 |
LPHN3 | LRRIQ3 | ENSP00000422533 | ENSP00000346414 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | Leucine rich repeats and IQ motif containing 3 | 0.683 |
LRRIQ3 | ENSG00000259030 | ENSP00000346414 | ENSP00000450895 | Leucine rich repeats and IQ motif containing 3 | FPGT-TNNI3K readthrough; Ankyrin repeat domain containing | 0.819 |
LRRIQ3 | FPGT | ENSP00000346414 | ENSP00000359935 | Leucine rich repeats and IQ motif containing 3 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids | 0.752 |
LRRIQ3 | LPHN1 | ENSP00000346414 | ENSP00000340688 | Leucine rich repeats and IQ motif containing 3 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | 0.683 |
LRRIQ3 | LPHN2 | ENSP00000346414 | ENSP00000322270 | Leucine rich repeats and IQ motif containing 3 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | 0.683 |
LRRIQ3 | LPHN3 | ENSP00000346414 | ENSP00000422533 | Leucine rich repeats and IQ motif containing 3 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | 0.683 |
LRRIQ3 | R3HCC1L | ENSP00000346414 | ENSP00000483494 | Leucine rich repeats and IQ motif containing 3 | Coiled-coil domain-containing protein R3HCC1L; R3H domain and coiled-coil containing 1 like | 0.698 |
LRRIQ3 | SAMD5 | ENSP00000346414 | ENSP00000356444 | Leucine rich repeats and IQ motif containing 3 | Sterile alpha motif domain containing 5 | 0.709 |
LRRIQ3 | TMC7 | ENSP00000346414 | ENSP00000455041 | Leucine rich repeats and IQ motif containing 3 | Transmembrane channel-like protein 7; Probable ion channel; Transmembrane channel likes | 0.770 |
LRRIQ3 | TNNI3K | ENSP00000346414 | ENSP00000322251 | Leucine rich repeats and IQ motif containing 3 | Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily | 0.775 |
LRRIQ3 | ZNF33B | ENSP00000346414 | ENSP00000352444 | Leucine rich repeats and IQ motif containing 3 | Zinc finger protein 33B; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.713 |
R3HCC1L | LRRIQ3 | ENSP00000483494 | ENSP00000346414 | Coiled-coil domain-containing protein R3HCC1L; R3H domain and coiled-coil containing 1 like | Leucine rich repeats and IQ motif containing 3 | 0.698 |
SAMD5 | LRRIQ3 | ENSP00000356444 | ENSP00000346414 | Sterile alpha motif domain containing 5 | Leucine rich repeats and IQ motif containing 3 | 0.709 |