node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDOA | ALDOB | ENSP00000378669 | ENSP00000363988 | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | Aldolase, fructose-bisphosphate B | 0.818 |
ALDOA | ALDOC | ENSP00000378669 | ENSP00000226253 | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | Aldolase, fructose-bisphosphate C | 0.981 |
ALDOA | GPI | ENSP00000378669 | ENSP00000405573 | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | Glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons | 0.969 |
ALDOA | PFKFB3 | ENSP00000378669 | ENSP00000443319 | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; Synthesis and degradation of fructose 2,6-bisphosphate; In the C-terminal section; belongs to the phosphoglycerate mutase family | 0.505 |
ALDOA | PFKL | ENSP00000378669 | ENSP00000269848 | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | ATP-dependent 6-phosphofructokinase, liver type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily | 0.978 |
ALDOA | PFKM | ENSP00000378669 | ENSP00000345771 | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | ATP-dependent 6-phosphofructokinase, muscle type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily | 0.976 |
ALDOA | PFKP | ENSP00000378669 | ENSP00000370517 | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | ATP-dependent 6-phosphofructokinase, platelet type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily | 0.979 |
ALDOA | TALDO1 | ENSP00000378669 | ENSP00000321259 | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway | 0.975 |
ALDOA | TKT | ENSP00000378669 | ENSP00000391481 | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate; Belongs to the transketolase family | 0.973 |
ALDOB | ALDOA | ENSP00000363988 | ENSP00000378669 | Aldolase, fructose-bisphosphate B | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | 0.818 |
ALDOB | ALDOC | ENSP00000363988 | ENSP00000226253 | Aldolase, fructose-bisphosphate B | Aldolase, fructose-bisphosphate C | 0.806 |
ALDOB | GPI | ENSP00000363988 | ENSP00000405573 | Aldolase, fructose-bisphosphate B | Glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons | 0.947 |
ALDOB | PFKL | ENSP00000363988 | ENSP00000269848 | Aldolase, fructose-bisphosphate B | ATP-dependent 6-phosphofructokinase, liver type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily | 0.976 |
ALDOB | PFKM | ENSP00000363988 | ENSP00000345771 | Aldolase, fructose-bisphosphate B | ATP-dependent 6-phosphofructokinase, muscle type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily | 0.970 |
ALDOB | PFKP | ENSP00000363988 | ENSP00000370517 | Aldolase, fructose-bisphosphate B | ATP-dependent 6-phosphofructokinase, platelet type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily | 0.975 |
ALDOB | TALDO1 | ENSP00000363988 | ENSP00000321259 | Aldolase, fructose-bisphosphate B | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway | 0.952 |
ALDOB | TKT | ENSP00000363988 | ENSP00000391481 | Aldolase, fructose-bisphosphate B | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate; Belongs to the transketolase family | 0.949 |
ALDOC | ALDOA | ENSP00000226253 | ENSP00000378669 | Aldolase, fructose-bisphosphate C | Fructose-bisphosphate aldolase A; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity); Belongs to the class I fructose-bisphosphate aldolase family | 0.981 |
ALDOC | ALDOB | ENSP00000226253 | ENSP00000363988 | Aldolase, fructose-bisphosphate C | Aldolase, fructose-bisphosphate B | 0.806 |
ALDOC | GPI | ENSP00000226253 | ENSP00000405573 | Aldolase, fructose-bisphosphate C | Glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons | 0.944 |