• Version:
  • 11.0 [archived version]
STRINGSTRING
OPALIN OPALIN PRR18 PRR18 FRRS1L FRRS1L CCDC120 CCDC120 AMER3 AMER3 CMTM5 CMTM5 CMTM8 CMTM8 CMTM2 CMTM2 CMTM4 CMTM4 CMTM7 CMTM7 CKLF CKLF
"CMTM5" - CKLF like MARVEL transmembrane domain containing 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CMTM5CKLF like MARVEL transmembrane domain containing 5; Belongs to the chemokine-like factor family (223 aa)    
Predicted Functional Partners:
CKLF
Chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10 (152 aa)
           
  0.890
CMTM8
CKLF like MARVEL transmembrane domain containing 8; Belongs to the chemokine-like factor family (173 aa)
           
  0.769
CMTM4
CKLF like MARVEL transmembrane domain containing 4 (234 aa)
           
  0.716
PRR18
Proline-rich protein 18; Proline rich 18 (295 aa)
     
   
  0.671
CMTM7
CKLF like MARVEL transmembrane domain containing 7; Belongs to the chemokine-like factor family (175 aa)
           
  0.602
CMTM2
CKLF like MARVEL transmembrane domain containing 2; Belongs to the chemokine-like factor family (248 aa)
     
   
  0.558
CCDC120
Coiled-coil domain-containing protein 120; Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells. Together with CCDC68, cooperate with subdistal appendage components ODF2, NIN and CEP170 for hierarchical subdistal appendage assembly. Recruits NIN and CEP170 to centrosomes. Also required for neurite growth. Localizes CYTH2 to vesicles to allow its transport along neurites, and subsequent ARF6 activation and neurite growth (696 aa)
           
  0.547
FRRS1L
DOMON domain-containing protein FRRS1L; Important modulator of glutamate signaling pathway (344 aa)
     
   
  0.546
AMER3
APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) (861 aa)
     
   
  0.526
OPALIN
Opalin; Oligodendrocytic myelin paranodal and inner loop protein (141 aa)
     
   
  0.512
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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