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  • 11.0 [archived version]
STRINGSTRING
RAD9B RAD9B ANKS1B ANKS1B ACOT6 ACOT6 TRIM28 TRIM28 ZNF69 ZNF69 YPEL5 YPEL5 ZNF600 ZNF600 PPWD1 PPWD1 TMEM217 TMEM217 SLC5A9 SLC5A9 FAM132A FAM132A
"ZNF600" - Zinc finger protein 600 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF600Zinc finger protein 600; May be involved in transcriptional regulation; Zinc fingers C2H2-type (722 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.908
ZNF69
Zinc finger protein 69; Zinc fingers C2H2-type (149 aa)
           
  0.546
TMEM217
Transmembrane protein 217 (229 aa)
           
  0.530
ACOT6
acyl-CoA thioesterase 6 (207 aa)
     
   
  0.503
PPWD1
Peptidylprolyl isomerase domain and WD repeat-containing protein 1; Putative peptidylprolyl isomerase (PPIase). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing; Cyclophilin peptidylprolyl isomerases (646 aa)
     
 
  0.486
RAD9B
Cell cycle checkpoint control protein RAD9B; RAD9 checkpoint clamp component B (429 aa)
           
  0.479
ANKS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B; Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells; Ankyrin repeat domain containing (1248 aa)
     
 
  0.450
SLC5A9
Sodium/glucose cotransporter 4; Involved in sodium-dependent transport of D-mannose, D- glucose and D-fructose; Belongs to the sodium-solute symporter (SSF) (TC 2.A.21) family (706 aa)
           
  0.442
YPEL5
Protein yippee-like 5; Yippee like family; Belongs to the yippee family (121 aa)
           
  0.440
FAM132A
Adipolin; Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue (302 aa)
           
  0.429
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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