• Version:
  • 11.0 [archived version]
STRINGSTRING
FAM163A FAM163A RGS21 RGS21 RGS1 RGS1 ZNF648 ZNF648 RTCA RTCA KLK9 KLK9 KLK12 KLK12 ABCA13 ABCA13 TIGD7 TIGD7 TIGD6 TIGD6 OR52N4 OR52N4
"ZNF648" - Zinc finger protein 648 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
ZNF648Zinc finger protein 648; May be involved in transcriptional regulation; Zinc fingers C2H2-type (568 aa)    
Predicted Functional Partners:
TIGD7
Tigger transposable element-derived protein 7; Helix-turn-helix CENPB type domain containing; Belongs to the tigger transposable element derived protein family (549 aa)
       
 
  0.745
KLK9
Kallikrein-9; Kallikrein related peptidase 9; Kallikreins (250 aa)
           
  0.666
OR52N4
Olfactory receptor 52N4; Odorant receptor; Olfactory receptors, family 52 (321 aa)
           
  0.581
ABCA13
ATP binding cassette subfamily A member 13 (5058 aa)
     
 
  0.569
KLK12
Kallikrein-12; Kallikrein related peptidase 12; Belongs to the peptidase S1 family. Kallikrein subfamily (254 aa)
           
  0.564
RGS1
Regulator of G-protein signaling 1; Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors. Inhibits B cell chemotaxis toward CXCL12 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (209 aa)
       
 
  0.548
TIGD6
Tigger transposable element-derived protein 6; Helix-turn-helix CENPB type domain containing; DNA transposon derived genes (521 aa)
       
 
  0.540
RGS21
Regulator of G-protein signaling 21; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form; Regulators of G-protein signaling (152 aa)
       
 
  0.494
FAM163A
Protein FAM163A; Family with sequence similarity 163 member A; Belongs to the FAM163 family (167 aa)
           
  0.480
RTCA
RNA 3’-terminal phosphate cyclase; Catalyzes the conversion of 3’-phosphate to a 2’,3’- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps- (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3’P to produce RNA- N3’PP5’A; (C) and attack of the adjacent 2’-hydroxyl on the 3’- phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing; Belongs to the RNA 3’-terminal cyclase family. Type 1 subfamily (379 aa)
           
  0.446
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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