SYNGR4 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SYNGR4

Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins (234 aa)

Predicted Functional Partners:

SYNPR

0.770

TULP2

0.749

SPACA4

0.728

CMTM4

0.626

SV2A

0.595

SYP

0.575

SYPL2

0.537

ATP6V0A1

0.520

RAB3A

0.514

SULT2A1

0.505

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0A1	SYNGR4	ENSP00000264649	ENSP00000344041	V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity); V-type ATPases	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	0.520
CMTM4	SYNGR4	ENSP00000333833	ENSP00000344041	CKLF like MARVEL transmembrane domain containing 4	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	0.626
RAB3A	SV2A	ENSP00000222256	ENSP00000358142	Ras-related protein Rab-3A; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal; RAB, member RAS oncogene GTPases	Synaptic vesicle glycoprotein 2A; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)	0.640
RAB3A	SYNGR4	ENSP00000222256	ENSP00000344041	Ras-related protein Rab-3A; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal; RAB, member RAS oncogene GTPases	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	0.514
RAB3A	SYNPR	ENSP00000222256	ENSP00000418994	Ras-related protein Rab-3A; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal; RAB, member RAS oncogene GTPases	Synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity); Belongs to the synaptophysin/synaptobrevin family	0.446
RAB3A	SYP	ENSP00000222256	ENSP00000263233	Ras-related protein Rab-3A; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal; RAB, member RAS oncogene GTPases	Synaptophysin; Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity); Synaptophysins	0.786
SPACA4	SYNGR4	ENSP00000312774	ENSP00000344041	Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization; LY6/PLAUR domain containing	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	0.728
SPACA4	TULP2	ENSP00000312774	ENSP00000221399	Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization; LY6/PLAUR domain containing	Tubby like protein 2; Belongs to the TUB family	0.558
SULT2A1	SYNGR4	ENSP00000222002	ENSP00000344041	Bile salt sulfotransferase; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands; Sulfotransferases, cytosolic	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	0.505
SULT2A1	TULP2	ENSP00000222002	ENSP00000221399	Bile salt sulfotransferase; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands; Sulfotransferases, cytosolic	Tubby like protein 2; Belongs to the TUB family	0.432
SV2A	RAB3A	ENSP00000358142	ENSP00000222256	Synaptic vesicle glycoprotein 2A; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)	Ras-related protein Rab-3A; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal; RAB, member RAS oncogene GTPases	0.640
SV2A	SYNGR4	ENSP00000358142	ENSP00000344041	Synaptic vesicle glycoprotein 2A; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	0.595
SV2A	SYNPR	ENSP00000358142	ENSP00000418994	Synaptic vesicle glycoprotein 2A; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)	Synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity); Belongs to the synaptophysin/synaptobrevin family	0.470
SV2A	SYP	ENSP00000358142	ENSP00000263233	Synaptic vesicle glycoprotein 2A; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)	Synaptophysin; Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity); Synaptophysins	0.799
SYNGR4	ATP6V0A1	ENSP00000344041	ENSP00000264649	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity); V-type ATPases	0.520
SYNGR4	CMTM4	ENSP00000344041	ENSP00000333833	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	CKLF like MARVEL transmembrane domain containing 4	0.626
SYNGR4	RAB3A	ENSP00000344041	ENSP00000222256	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	Ras-related protein Rab-3A; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal; RAB, member RAS oncogene GTPases	0.514
SYNGR4	SPACA4	ENSP00000344041	ENSP00000312774	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization; LY6/PLAUR domain containing	0.728
SYNGR4	SULT2A1	ENSP00000344041	ENSP00000222002	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	Bile salt sulfotransferase; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands; Sulfotransferases, cytosolic	0.505
SYNGR4	SV2A	ENSP00000344041	ENSP00000358142	Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins	Synaptic vesicle glycoprotein 2A; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)	0.595

page 1 of 2

Network

Cooccurrence

Experiments

Coexpression

Textmining

Neighborhood

Databases

Fusion

© STRING Consortium 2020

Credits

Access

Info

About