MRRF protein (human) - STRING database

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MRRF

Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) (262 aa)

Predicted Functional Partners:

GFM2

0.994

MRPS9

0.992

MRPL20

0.991

MRPS16

0.991

MRPL19

0.990

MRPL1

0.990

MRPS10

0.989

MRPL13

0.987

MRPL27

0.986

MRPL21

0.986

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GFM2	MRPL1	ENSP00000296805	ENSP00000315017	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein L1	0.906
GFM2	MRPL13	ENSP00000296805	ENSP00000306548	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	0.975
GFM2	MRPL19	ENSP00000296805	ENSP00000377486	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family	0.979
GFM2	MRPL20	ENSP00000296805	ENSP00000341082	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein L20	0.983
GFM2	MRPL21	ENSP00000296805	ENSP00000354580	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein L21	0.973
GFM2	MRPL27	ENSP00000296805	ENSP00000225969	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein L27	0.982
GFM2	MRPS10	ENSP00000296805	ENSP00000053468	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family	0.970
GFM2	MRPS16	ENSP00000296805	ENSP00000362036	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family	0.979
GFM2	MRPS9	ENSP00000296805	ENSP00000258455	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein S9	0.979
GFM2	MRRF	ENSP00000296805	ENSP00000343867	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)	0.994
MRPL1	GFM2	ENSP00000315017	ENSP00000296805	Mitochondrial ribosomal protein L1	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	0.906
MRPL1	MRPL13	ENSP00000315017	ENSP00000306548	Mitochondrial ribosomal protein L1	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	0.999
MRPL1	MRPL19	ENSP00000315017	ENSP00000377486	Mitochondrial ribosomal protein L1	Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family	0.999
MRPL1	MRPL20	ENSP00000315017	ENSP00000341082	Mitochondrial ribosomal protein L1	Mitochondrial ribosomal protein L20	0.998
MRPL1	MRPL21	ENSP00000315017	ENSP00000354580	Mitochondrial ribosomal protein L1	Mitochondrial ribosomal protein L21	0.995
MRPL1	MRPL27	ENSP00000315017	ENSP00000225969	Mitochondrial ribosomal protein L1	Mitochondrial ribosomal protein L27	0.999
MRPL1	MRPS10	ENSP00000315017	ENSP00000053468	Mitochondrial ribosomal protein L1	Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family	0.990
MRPL1	MRPS16	ENSP00000315017	ENSP00000362036	Mitochondrial ribosomal protein L1	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family	0.996
MRPL1	MRPS9	ENSP00000315017	ENSP00000258455	Mitochondrial ribosomal protein L1	Mitochondrial ribosomal protein S9	0.994
MRPL1	MRRF	ENSP00000315017	ENSP00000343867	Mitochondrial ribosomal protein L1	Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)	0.990

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