TLDC1 protein (human) - STRING database

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TLDC1

TLD domain-containing protein 1; TBC/LysM-associated domain containing 1 (456 aa)

Predicted Functional Partners:

HDHD3

0.760

PATZ1

0.726

RAB3GAP2

0.689

ZZEF1

0.658

SCRN3

0.653

SDR42E1

0.643

ZNF639

0.573

DNAJC16

0.556

TBC1D24

0.555

HABP4

0.509

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNAJC16	HABP4	ENSP00000365007	ENSP00000364398	DnaJ heat shock protein family member C16	Intracellular hyaluronan-binding protein 4; RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity). Plays a role in pre-mRNA splicing regulation. Binds (via C-terminus) to poly(U) RNA. Involved in mRNA translation regulation, probably at the initiation step	0.474
DNAJC16	SCRN3	ENSP00000365007	ENSP00000272732	DnaJ heat shock protein family member C16	Secernin-3; Secernin 3	0.480
DNAJC16	TLDC1	ENSP00000365007	ENSP00000343635	DnaJ heat shock protein family member C16	TLD domain-containing protein 1; TBC/LysM-associated domain containing 1	0.556
DNAJC16	ZNF639	ENSP00000365007	ENSP00000325634	DnaJ heat shock protein family member C16	Zinc finger protein 639; Binds DNA and may function as a transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family	0.458
HABP4	DNAJC16	ENSP00000364398	ENSP00000365007	Intracellular hyaluronan-binding protein 4; RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity). Plays a role in pre-mRNA splicing regulation. Binds (via C-terminus) to poly(U) RNA. Involved in mRNA translation regulation, probably at the initiation step	DnaJ heat shock protein family member C16	0.474
HABP4	SCRN3	ENSP00000364398	ENSP00000272732	Intracellular hyaluronan-binding protein 4; RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity). Plays a role in pre-mRNA splicing regulation. Binds (via C-terminus) to poly(U) RNA. Involved in mRNA translation regulation, probably at the initiation step	Secernin-3; Secernin 3	0.523
HABP4	TLDC1	ENSP00000364398	ENSP00000343635	Intracellular hyaluronan-binding protein 4; RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity). Plays a role in pre-mRNA splicing regulation. Binds (via C-terminus) to poly(U) RNA. Involved in mRNA translation regulation, probably at the initiation step	TLD domain-containing protein 1; TBC/LysM-associated domain containing 1	0.509
HABP4	ZNF639	ENSP00000364398	ENSP00000325634	Intracellular hyaluronan-binding protein 4; RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity). Plays a role in pre-mRNA splicing regulation. Binds (via C-terminus) to poly(U) RNA. Involved in mRNA translation regulation, probably at the initiation step	Zinc finger protein 639; Binds DNA and may function as a transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family	0.445
HDHD3	PATZ1	ENSP00000238379	ENSP00000266269	Haloacid dehalogenase like hydrolase domain containing 3	POZ-, AT hook-, and zinc finger-containing protein 1; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family	0.646
HDHD3	TLDC1	ENSP00000238379	ENSP00000343635	Haloacid dehalogenase like hydrolase domain containing 3	TLD domain-containing protein 1; TBC/LysM-associated domain containing 1	0.760
PATZ1	HDHD3	ENSP00000266269	ENSP00000238379	POZ-, AT hook-, and zinc finger-containing protein 1; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family	Haloacid dehalogenase like hydrolase domain containing 3	0.646
PATZ1	TLDC1	ENSP00000266269	ENSP00000343635	POZ-, AT hook-, and zinc finger-containing protein 1; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family	TLD domain-containing protein 1; TBC/LysM-associated domain containing 1	0.726
RAB3GAP2	TLDC1	ENSP00000351832	ENSP00000343635	Rab3 GTPase-activating protein non-catalytic subunit; Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3- GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non- synaptic vesicular release of neurotransmitters	TLD domain-containing protein 1; TBC/LysM-associated domain containing 1	0.689
SCRN3	DNAJC16	ENSP00000272732	ENSP00000365007	Secernin-3; Secernin 3	DnaJ heat shock protein family member C16	0.480
SCRN3	HABP4	ENSP00000272732	ENSP00000364398	Secernin-3; Secernin 3	Intracellular hyaluronan-binding protein 4; RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity). Plays a role in pre-mRNA splicing regulation. Binds (via C-terminus) to poly(U) RNA. Involved in mRNA translation regulation, probably at the initiation step	0.523
SCRN3	TLDC1	ENSP00000272732	ENSP00000343635	Secernin-3; Secernin 3	TLD domain-containing protein 1; TBC/LysM-associated domain containing 1	0.653
SCRN3	ZNF639	ENSP00000272732	ENSP00000325634	Secernin-3; Secernin 3	Zinc finger protein 639; Binds DNA and may function as a transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family	0.584
SDR42E1	TLDC1	ENSP00000332407	ENSP00000343635	Short chain dehydrogenase/reductase family 42E, member 1	TLD domain-containing protein 1; TBC/LysM-associated domain containing 1	0.643
TBC1D24	TLDC1	ENSP00000293970	ENSP00000343635	TBC1 domain family member 24; May act as a GTPase-activating protein for Rab family protein(s). Involved in neuronal projections development, probably through a negative modulation of ARF6 function; Deafness associated genes	TLD domain-containing protein 1; TBC/LysM-associated domain containing 1	0.555
TLDC1	DNAJC16	ENSP00000343635	ENSP00000365007	TLD domain-containing protein 1; TBC/LysM-associated domain containing 1	DnaJ heat shock protein family member C16	0.556

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