node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHDC1 | ARHGEF10L | ENSP00000363123 | ENSP00000355060 | AT-hook DNA-binding motif-containing protein 1; AT-hook DNA binding motif containing 1 | Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC | 0.426 |
AHDC1 | KCTD19 | ENSP00000363123 | ENSP00000305702 | AT-hook DNA-binding motif-containing protein 1; AT-hook DNA binding motif containing 1 | BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19 | 0.453 |
AHDC1 | ZFP30 | ENSP00000363123 | ENSP00000343581 | AT-hook DNA-binding motif-containing protein 1; AT-hook DNA binding motif containing 1 | Zinc finger protein 30 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.476 |
ARHGEF10L | AHDC1 | ENSP00000355060 | ENSP00000363123 | Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC | AT-hook DNA-binding motif-containing protein 1; AT-hook DNA binding motif containing 1 | 0.426 |
ARHGEF10L | KCTD19 | ENSP00000355060 | ENSP00000305702 | Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC | BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19 | 0.422 |
ARHGEF10L | ZFP30 | ENSP00000355060 | ENSP00000343581 | Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC | Zinc finger protein 30 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.443 |
ATOH8 | ZFP30 | ENSP00000304676 | ENSP00000343581 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5’-CANNTG- 3’ known as an E-box element, possibly as a heterodimer with other bHLH proteins. Regulates endothelial cell proliferation, migration and tube-like structures formation. Modulates endothelial cell differentiation through NOS3. May be implicated in specification and differentiation of neuronal cell lineages in the brain (By similarity). May participate in kidney development and may be involved in podocyte differentiation (By similarity). During early embryonic devel [...] | Zinc finger protein 30 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.491 |
FAM69C | LRRC14 | ENSP00000344331 | ENSP00000292524 | Protein FAM69C; Family with sequence similarity 69 member C | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily | 0.461 |
FAM69C | SPATA32 | ENSP00000344331 | ENSP00000331532 | Protein FAM69C; Family with sequence similarity 69 member C | Spermatogenesis-associated protein 32; Spermatogenesis associated 32 | 0.543 |
FAM69C | TCP11L2 | ENSP00000344331 | ENSP00000299045 | Protein FAM69C; Family with sequence similarity 69 member C | T-complex protein 11-like protein 2; T-complex 11 like 2 | 0.505 |
FAM69C | ZFP30 | ENSP00000344331 | ENSP00000343581 | Protein FAM69C; Family with sequence similarity 69 member C | Zinc finger protein 30 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.499 |
JADE1 | TCP11L2 | ENSP00000226319 | ENSP00000299045 | Protein Jade-1; Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function; PHD finger proteins | T-complex protein 11-like protein 2; T-complex 11 like 2 | 0.465 |
JADE1 | ZFP30 | ENSP00000226319 | ENSP00000343581 | Protein Jade-1; Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function; PHD finger proteins | Zinc finger protein 30 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.460 |
KCTD19 | AHDC1 | ENSP00000305702 | ENSP00000363123 | BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19 | AT-hook DNA-binding motif-containing protein 1; AT-hook DNA binding motif containing 1 | 0.453 |
KCTD19 | ARHGEF10L | ENSP00000305702 | ENSP00000355060 | BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19 | Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC | 0.422 |
KCTD19 | ZFP30 | ENSP00000305702 | ENSP00000343581 | BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19 | Zinc finger protein 30 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.480 |
LRRC14 | FAM69C | ENSP00000292524 | ENSP00000344331 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily | Protein FAM69C; Family with sequence similarity 69 member C | 0.461 |
LRRC14 | SPATA32 | ENSP00000292524 | ENSP00000331532 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily | Spermatogenesis-associated protein 32; Spermatogenesis associated 32 | 0.440 |
LRRC14 | TCP11L2 | ENSP00000292524 | ENSP00000299045 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily | T-complex protein 11-like protein 2; T-complex 11 like 2 | 0.455 |
LRRC14 | ZFP30 | ENSP00000292524 | ENSP00000343581 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily | Zinc finger protein 30 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.479 |