• Version:
  • 11.0 [archived version]
STRINGSTRING
ATOH8 ATOH8 AHDC1 AHDC1 ARHGEF10L ARHGEF10L KCTD19 KCTD19 FAM69C FAM69C ZFP30 ZFP30 LRRC14 LRRC14 SPATA32 SPATA32 TRIM28 TRIM28 TCP11L2 TCP11L2 JADE1 JADE1
"ZFP30" - Zinc finger protein 30 homolog in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZFP30Zinc finger protein 30 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type (519 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.904
FAM69C
Protein FAM69C; Family with sequence similarity 69 member C (419 aa)
           
  0.499
ATOH8
Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5’-CANNTG- 3’ known as an E-box element, possibly as a heterodimer with other bHLH proteins. Regulates endothelial cell proliferation, migration and tube-like structures formation. Modulates endothelial cell differentiation through NOS3. May be implicated in specification and differentiation of neuronal cell lineages in the brain (By similarity). May participate in kidney development and may be involved in podocyte differentiation (By similarity). During early embryonic devel [...] (321 aa)
       
 
  0.491
TCP11L2
T-complex protein 11-like protein 2; T-complex 11 like 2 (519 aa)
           
  0.484
KCTD19
BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19 (926 aa)
       
 
  0.480
LRRC14
Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily (493 aa)
           
  0.479
AHDC1
AT-hook DNA-binding motif-containing protein 1; AT-hook DNA binding motif containing 1 (1603 aa)
           
  0.476
SPATA32
Spermatogenesis-associated protein 32; Spermatogenesis associated 32 (384 aa)
           
  0.473
JADE1
Protein Jade-1; Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function; PHD finger proteins (842 aa)
     
 
  0.460
ARHGEF10L
Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC (1279 aa)
           
  0.443
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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