• Version:
  • 11.0 [archived version]
STRINGSTRING
DUSP27 DUSP27 FAM134C FAM134C HTR1A HTR1A YIPF5 YIPF5 YIF1B YIF1B ESYT1 ESYT1 IER3IP1 IER3IP1 YIPF6 YIPF6 DERL1 DERL1 YIPF7 YIPF7 DUPD1 DUPD1
"YIF1B" - Protein YIF1B in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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YIF1BProtein YIF1B; Yip1 interacting factor homolog B, membrane trafficking protein; Belongs to the YIF1 family (314 aa)    
Predicted Functional Partners:
ESYT1
Extended synaptotagmin-1; Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane; Belongs to the extended synaptotagmin family (1114 aa)
       
 
  0.889
DERL1
Derlin-1; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the misfolded protein. Also involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for prot [...] (251 aa)
     
 
  0.865
YIPF7
Protein YIPF7; Yip1 domain family member 7; Belongs to the YIP1 family (280 aa)
     
 
  0.824
YIPF5
Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Yip1 domain containing (257 aa)
     
 
  0.795
DUSP27
Inactive dual specificity phosphatase 27; May be required for myofiber maturation (1158 aa)
     
   
  0.740
YIPF6
Protein YIPF6; May be required for stable YIPF1 and YIPF2 protein expression; Yip1 domain containing (236 aa)
     
 
  0.711
DUPD1
Dual specificity phosphatase DUPD1; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate (220 aa)
     
   
  0.674
HTR1A
5-hydroxytryptamine receptor 1A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second [...] (422 aa)
           
  0.654
FAM134C
Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth; Belongs to the RETREG family (466 aa)
           
  0.642
IER3IP1
Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) (82 aa)
     
 
  0.607
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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