| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MN1 | VSTM1 | ENSP00000304956 | ENSP00000343366 | Transcriptional activator MN1; Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate. Required during later stages of palate development for growth and medial fusion of the palatal shelves. Promotes maturation and normal function of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL. Necessary for normal development of the membranous bones of the skull (By similarity). May play a role in tumor suppression (Probable) | V-set and transmembrane domain-containing protein 1; Isoform 2- Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17); Immunoglobulin like domain containing | 0.453 |
| NDUFA3 | PRPF31 | ENSP00000418438 | ENSP00000324122 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH-ubiquinone oxidoreductase supernumerary subunits | U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome; U4/U6 small nucleolar ribonucleoprotein | 0.576 |
| NDUFA3 | RDH13 | ENSP00000418438 | ENSP00000391121 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH-ubiquinone oxidoreductase supernumerary subunits | Retinol dehydrogenase 13; Does not exhibit retinol dehydrogenase (RDH) activity in vitro; Short chain dehydrogenase/reductase superfamily | 0.433 |
| NDUFA3 | TFPT | ENSP00000418438 | ENSP00000375639 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH-ubiquinone oxidoreductase supernumerary subunits | TCF3 fusion partner; Appears to promote apoptosis in a p53/TP53-independent manner; INO80 complex | 0.732 |
| NDUFA3 | VSTM1 | ENSP00000418438 | ENSP00000343366 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH-ubiquinone oxidoreductase supernumerary subunits | V-set and transmembrane domain-containing protein 1; Isoform 2- Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17); Immunoglobulin like domain containing | 0.508 |
| PIK3IP1 | VSTM1 | ENSP00000215912 | ENSP00000343366 | Phosphoinositide-3-kinase-interacting protein 1; Negative regulator of hepatic phosphatidylinositol 3- kinase (PI3K) activity | V-set and transmembrane domain-containing protein 1; Isoform 2- Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17); Immunoglobulin like domain containing | 0.456 |
| PRPF31 | NDUFA3 | ENSP00000324122 | ENSP00000418438 | U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome; U4/U6 small nucleolar ribonucleoprotein | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH-ubiquinone oxidoreductase supernumerary subunits | 0.576 |
| PRPF31 | TFPT | ENSP00000324122 | ENSP00000375639 | U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome; U4/U6 small nucleolar ribonucleoprotein | TCF3 fusion partner; Appears to promote apoptosis in a p53/TP53-independent manner; INO80 complex | 0.810 |
| PRPF31 | VSTM1 | ENSP00000324122 | ENSP00000343366 | U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome; U4/U6 small nucleolar ribonucleoprotein | V-set and transmembrane domain-containing protein 1; Isoform 2- Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17); Immunoglobulin like domain containing | 0.474 |
| RDH13 | NDUFA3 | ENSP00000391121 | ENSP00000418438 | Retinol dehydrogenase 13; Does not exhibit retinol dehydrogenase (RDH) activity in vitro; Short chain dehydrogenase/reductase superfamily | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH-ubiquinone oxidoreductase supernumerary subunits | 0.433 |
| RDH13 | TFPT | ENSP00000391121 | ENSP00000375639 | Retinol dehydrogenase 13; Does not exhibit retinol dehydrogenase (RDH) activity in vitro; Short chain dehydrogenase/reductase superfamily | TCF3 fusion partner; Appears to promote apoptosis in a p53/TP53-independent manner; INO80 complex | 0.581 |
| RDH13 | VSTM1 | ENSP00000391121 | ENSP00000343366 | Retinol dehydrogenase 13; Does not exhibit retinol dehydrogenase (RDH) activity in vitro; Short chain dehydrogenase/reductase superfamily | V-set and transmembrane domain-containing protein 1; Isoform 2- Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17); Immunoglobulin like domain containing | 0.455 |
| SNRNP25 | UBQLNL | ENSP00000372482 | ENSP00000369531 | Small nuclear ribonucleoprotein U11/U12 subunit 25 | Ubiquilin-like protein; Ubiquilin family | 0.434 |
| SNRNP25 | VSTM1 | ENSP00000372482 | ENSP00000343366 | Small nuclear ribonucleoprotein U11/U12 subunit 25 | V-set and transmembrane domain-containing protein 1; Isoform 2- Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17); Immunoglobulin like domain containing | 0.448 |
| TFPT | NDUFA3 | ENSP00000375639 | ENSP00000418438 | TCF3 fusion partner; Appears to promote apoptosis in a p53/TP53-independent manner; INO80 complex | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH-ubiquinone oxidoreductase supernumerary subunits | 0.732 |
| TFPT | PRPF31 | ENSP00000375639 | ENSP00000324122 | TCF3 fusion partner; Appears to promote apoptosis in a p53/TP53-independent manner; INO80 complex | U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome; U4/U6 small nucleolar ribonucleoprotein | 0.810 |
| TFPT | RDH13 | ENSP00000375639 | ENSP00000391121 | TCF3 fusion partner; Appears to promote apoptosis in a p53/TP53-independent manner; INO80 complex | Retinol dehydrogenase 13; Does not exhibit retinol dehydrogenase (RDH) activity in vitro; Short chain dehydrogenase/reductase superfamily | 0.581 |
| TFPT | VSTM1 | ENSP00000375639 | ENSP00000343366 | TCF3 fusion partner; Appears to promote apoptosis in a p53/TP53-independent manner; INO80 complex | V-set and transmembrane domain-containing protein 1; Isoform 2- Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17); Immunoglobulin like domain containing | 0.587 |
| TMEM8A | VSTM1 | ENSP00000401338 | ENSP00000343366 | Post-GPI attachment to proteins factor 6; Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchor proteins (GPI-AP). Has phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI. Required for the shedding of the GPI-AP TDGF1, but not CFC1, at the cell surface. Shedding of TDGF1 modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. Also indirectly involved in the tr [...] | V-set and transmembrane domain-containing protein 1; Isoform 2- Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17); Immunoglobulin like domain containing | 0.414 |
| UBQLNL | SNRNP25 | ENSP00000369531 | ENSP00000372482 | Ubiquilin-like protein; Ubiquilin family | Small nuclear ribonucleoprotein U11/U12 subunit 25 | 0.434 |
