node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APBB2 | ARID3B | ENSP00000427211 | ENSP00000343126 | Amyloid-beta A4 precursor protein-binding family B member 2; May modulate the internalization of amyloid-beta precursor protein | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | 0.593 |
APBB2 | FUT8 | ENSP00000427211 | ENSP00000353910 | Amyloid-beta A4 precursor protein-binding family B member 2; May modulate the internalization of amyloid-beta precursor protein | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans; Belongs to the glycosyltransferase 23 family | 0.550 |
APBB2 | P4HA2 | ENSP00000427211 | ENSP00000384999 | Amyloid-beta A4 precursor protein-binding family B member 2; May modulate the internalization of amyloid-beta precursor protein | Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | 0.591 |
ARID3B | APBB2 | ENSP00000343126 | ENSP00000427211 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | Amyloid-beta A4 precursor protein-binding family B member 2; May modulate the internalization of amyloid-beta precursor protein | 0.593 |
ARID3B | FRMD4A | ENSP00000343126 | ENSP00000350032 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | FERM domain-containing protein 4A; Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (By similarity). Plays a redundant role with FRMD4B in epithelial polarization (By similarity). May regulate MAPT secretion by activating ARF6-signaling; FERM domain containing | 0.522 |
ARID3B | FUT8 | ENSP00000343126 | ENSP00000353910 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans; Belongs to the glycosyltransferase 23 family | 0.560 |
ARID3B | P4HA2 | ENSP00000343126 | ENSP00000384999 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | 0.574 |
ARID3B | RBL2 | ENSP00000343126 | ENSP00000262133 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | Retinoblastoma-like protein 2; Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 ’Lys- 20’ trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentiall [...] | 0.632 |
ARID3B | RBPJL | ENSP00000343126 | ENSP00000341243 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | Recombining binding protein suppressor of hairless-like protein; Putative transcription factor, which cooperates with EBNA2 to activate transcription; Belongs to the Su(H) family | 0.670 |
ARID3B | ROGDI | ENSP00000343126 | ENSP00000322832 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | Protein rogdi homolog; May act as a positive regulator of cell proliferation; Belongs to the rogdi family | 0.669 |
ARID3B | TLE2 | ENSP00000343126 | ENSP00000466542 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | Transducin-like enhancer protein 2; Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity); Belongs to the WD repeat Groucho/TLE family | 0.635 |
ARID3B | ZNF598 | ENSP00000343126 | ENSP00000411409 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | E3 ubiquitin-protein ligase ZNF598; E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation. Required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40S ribosomal protein RPS10/eS10, RPS20/uS10 and RPS3/uS3. Stalling precludes synthesis of a long poly-lysine tail and initiates the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide. Also acts as a component of the 4EHP-GYF2 complex, a multipr [...] | 0.525 |
ARID3B | ZNF792 | ENSP00000343126 | ENSP00000385099 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | Zinc finger protein 792; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.588 |
FRMD4A | ARID3B | ENSP00000350032 | ENSP00000343126 | FERM domain-containing protein 4A; Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (By similarity). Plays a redundant role with FRMD4B in epithelial polarization (By similarity). May regulate MAPT secretion by activating ARF6-signaling; FERM domain containing | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | 0.522 |
FRMD4A | ROGDI | ENSP00000350032 | ENSP00000322832 | FERM domain-containing protein 4A; Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (By similarity). Plays a redundant role with FRMD4B in epithelial polarization (By similarity). May regulate MAPT secretion by activating ARF6-signaling; FERM domain containing | Protein rogdi homolog; May act as a positive regulator of cell proliferation; Belongs to the rogdi family | 0.555 |
FUT8 | APBB2 | ENSP00000353910 | ENSP00000427211 | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans; Belongs to the glycosyltransferase 23 family | Amyloid-beta A4 precursor protein-binding family B member 2; May modulate the internalization of amyloid-beta precursor protein | 0.550 |
FUT8 | ARID3B | ENSP00000353910 | ENSP00000343126 | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans; Belongs to the glycosyltransferase 23 family | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | 0.560 |
FUT8 | P4HA2 | ENSP00000353910 | ENSP00000384999 | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans; Belongs to the glycosyltransferase 23 family | Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | 0.564 |
P4HA2 | APBB2 | ENSP00000384999 | ENSP00000427211 | Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | Amyloid-beta A4 precursor protein-binding family B member 2; May modulate the internalization of amyloid-beta precursor protein | 0.591 |
P4HA2 | ARID3B | ENSP00000384999 | ENSP00000343126 | Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A; AT-rich interaction domain containing | 0.574 |