B3GALTL protein (human) - STRING database

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B3GALTL

Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan (498 aa)

Predicted Functional Partners:

ADAMTSL1

0.981

ADAMTS9

0.975

SPON1

0.962

CFP

0.959

ADAMTSL2

0.955

ADAMTS17

0.955

ADAMTS10

0.954

ADAMTSL4

0.950

THBS2

0.948

THBS1

0.948

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTS10	ADAMTS17	ENSP00000270328	ENSP00000268070	A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues; ADAM metallopeptidases with thrombospondin type 1 motif	ADAM metallopeptidase with thrombospondin type 1 motif 17	0.919
ADAMTS10	ADAMTS9	ENSP00000270328	ENSP00000418735	A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues; ADAM metallopeptidases with thrombospondin type 1 motif	A disintegrin and metalloproteinase with thrombospondin motifs 9; Cleaves the large aggregating proteoglycans, aggrecan (at the ’1838-Glu-\|-Ala-1839’ site) and versican (at the ’1428- Glu-\|-Ala-1429’ site). Has a protease-independent function in promoting the transport from the endoplasmic reticulum to the Golgi apparatus of a variety of secretory cargos; ADAM metallopeptidases with thrombospondin type 1 motif	0.913
ADAMTS10	ADAMTSL1	ENSP00000270328	ENSP00000369921	A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues; ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS-like protein 1; I-set domain containing; ADAMTS like	0.922
ADAMTS10	ADAMTSL2	ENSP00000270328	ENSP00000346478	A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues; ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS-like protein 2; ADAMTS like 2	0.938
ADAMTS10	ADAMTSL4	ENSP00000270328	ENSP00000358035	A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues; ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS-like protein 4; Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis; ADAMTS like	0.932
ADAMTS10	B3GALTL	ENSP00000270328	ENSP00000343002	A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues; ADAM metallopeptidases with thrombospondin type 1 motif	Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan	0.954
ADAMTS10	CFP	ENSP00000270328	ENSP00000247153	A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues; ADAM metallopeptidases with thrombospondin type 1 motif	Properdin; A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes	0.901
ADAMTS10	SPON1	ENSP00000270328	ENSP00000460236	A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues; ADAM metallopeptidases with thrombospondin type 1 motif	Spondin-1; Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell	0.908
ADAMTS10	THBS1	ENSP00000270328	ENSP00000260356	A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues; ADAM metallopeptidases with thrombospondin type 1 motif	Thrombospondin-1; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity)	0.920
ADAMTS10	THBS2	ENSP00000270328	ENSP00000355751	A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues; ADAM metallopeptidases with thrombospondin type 1 motif	Thrombospondin-2; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties	0.904
ADAMTS17	ADAMTS10	ENSP00000268070	ENSP00000270328	ADAM metallopeptidase with thrombospondin type 1 motif 17	A disintegrin and metalloproteinase with thrombospondin motifs 10; Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues; ADAM metallopeptidases with thrombospondin type 1 motif	0.919
ADAMTS17	ADAMTS9	ENSP00000268070	ENSP00000418735	ADAM metallopeptidase with thrombospondin type 1 motif 17	A disintegrin and metalloproteinase with thrombospondin motifs 9; Cleaves the large aggregating proteoglycans, aggrecan (at the ’1838-Glu-\|-Ala-1839’ site) and versican (at the ’1428- Glu-\|-Ala-1429’ site). Has a protease-independent function in promoting the transport from the endoplasmic reticulum to the Golgi apparatus of a variety of secretory cargos; ADAM metallopeptidases with thrombospondin type 1 motif	0.919
ADAMTS17	ADAMTSL1	ENSP00000268070	ENSP00000369921	ADAM metallopeptidase with thrombospondin type 1 motif 17	ADAMTS-like protein 1; I-set domain containing; ADAMTS like	0.923
ADAMTS17	ADAMTSL2	ENSP00000268070	ENSP00000346478	ADAM metallopeptidase with thrombospondin type 1 motif 17	ADAMTS-like protein 2; ADAMTS like 2	0.929
ADAMTS17	ADAMTSL4	ENSP00000268070	ENSP00000358035	ADAM metallopeptidase with thrombospondin type 1 motif 17	ADAMTS-like protein 4; Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis; ADAMTS like	0.931
ADAMTS17	B3GALTL	ENSP00000268070	ENSP00000343002	ADAM metallopeptidase with thrombospondin type 1 motif 17	Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan	0.955
ADAMTS17	CFP	ENSP00000268070	ENSP00000247153	ADAM metallopeptidase with thrombospondin type 1 motif 17	Properdin; A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes	0.900
ADAMTS17	SPON1	ENSP00000268070	ENSP00000460236	ADAM metallopeptidase with thrombospondin type 1 motif 17	Spondin-1; Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell	0.903
ADAMTS17	THBS1	ENSP00000268070	ENSP00000260356	ADAM metallopeptidase with thrombospondin type 1 motif 17	Thrombospondin-1; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity)	0.925
ADAMTS17	THBS2	ENSP00000268070	ENSP00000355751	ADAM metallopeptidase with thrombospondin type 1 motif 17	Thrombospondin-2; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties	0.902

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