node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAMTS17 | LYSMD4 | ENSP00000268070 | ENSP00000342840 | ADAM metallopeptidase with thrombospondin type 1 motif 17 | LysM and putative peptidoglycan-binding domain-containing protein 4; LysM domain containing 4 | 0.426 |
C15orf52 | C17orf77 | ENSP00000453969 | ENSP00000329353 | Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 | Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 | 0.669 |
C15orf52 | FAM20A | ENSP00000453969 | ENSP00000468308 | Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 | Pseudokinase FAM20A; Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the ’matrix’ that guides the deposition of the enamel minerals | 0.440 |
C15orf52 | LOC81691 | ENSP00000453969 | ENSP00000261377 | Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 | Putative RNA exonuclease NEF-sp | 0.558 |
C15orf52 | LYSMD4 | ENSP00000453969 | ENSP00000342840 | Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 | LysM and putative peptidoglycan-binding domain-containing protein 4; LysM domain containing 4 | 0.658 |
C15orf52 | STK32B | ENSP00000453969 | ENSP00000282908 | Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 | Serine/threonine kinase 32B | 0.479 |
C15orf52 | TBC1D31 | ENSP00000453969 | ENSP00000287380 | Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 | TBC1 domain family member 31; WD repeat domain containing | 0.510 |
C15orf52 | TTC28 | ENSP00000453969 | ENSP00000381003 | Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 | Tetratricopeptide repeat protein 28; During mitosis, may be involved in the condensation of spindle midzone microtubules, leading to the formation of midbody; Tetratricopeptide repeat domain containing | 0.450 |
C17orf77 | C15orf52 | ENSP00000329353 | ENSP00000453969 | Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 | Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 | 0.669 |
C17orf77 | DERL2 | ENSP00000329353 | ENSP00000158771 | Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 | Derlin-2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and misfolded glycoproteins. May also be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the [...] | 0.440 |
C17orf77 | FAM20A | ENSP00000329353 | ENSP00000468308 | Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 | Pseudokinase FAM20A; Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the ’matrix’ that guides the deposition of the enamel minerals | 0.475 |
C17orf77 | LOC81691 | ENSP00000329353 | ENSP00000261377 | Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 | Putative RNA exonuclease NEF-sp | 0.589 |
C17orf77 | LYSMD4 | ENSP00000329353 | ENSP00000342840 | Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 | LysM and putative peptidoglycan-binding domain-containing protein 4; LysM domain containing 4 | 0.670 |
C17orf77 | NDST4 | ENSP00000329353 | ENSP00000264363 | Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity (By similarity); Belongs to the sulfotransferase 1 family. NDST subfamily | 0.441 |
C17orf77 | STK32B | ENSP00000329353 | ENSP00000282908 | Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 | Serine/threonine kinase 32B | 0.537 |
C17orf77 | TBC1D31 | ENSP00000329353 | ENSP00000287380 | Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 | TBC1 domain family member 31; WD repeat domain containing | 0.553 |
C17orf77 | TTC28 | ENSP00000329353 | ENSP00000381003 | Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 | Tetratricopeptide repeat protein 28; During mitosis, may be involved in the condensation of spindle midzone microtubules, leading to the formation of midbody; Tetratricopeptide repeat domain containing | 0.511 |
DERL2 | C17orf77 | ENSP00000158771 | ENSP00000329353 | Derlin-2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and misfolded glycoproteins. May also be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the [...] | Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 | 0.440 |
DERL2 | LYSMD4 | ENSP00000158771 | ENSP00000342840 | Derlin-2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and misfolded glycoproteins. May also be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the [...] | LysM and putative peptidoglycan-binding domain-containing protein 4; LysM domain containing 4 | 0.427 |
FAM20A | C15orf52 | ENSP00000468308 | ENSP00000453969 | Pseudokinase FAM20A; Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the ’matrix’ that guides the deposition of the enamel minerals | Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 | 0.440 |