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  • 11.0 [archived version]
STRINGSTRING
FAM20A FAM20A TBC1D31 TBC1D31 C15orf52 C15orf52 LOC81691 LOC81691 TTC28 TTC28 C17orf77 C17orf77 STK32B STK32B LYSMD4 LYSMD4 NDST4 NDST4 ADAMTS17 ADAMTS17 DERL2 DERL2
"LYSMD4" - LysM and putative peptidoglycan-binding domain-containing protein 4 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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LYSMD4LysM and putative peptidoglycan-binding domain-containing protein 4; LysM domain containing 4 (297 aa)    
Predicted Functional Partners:
C17orf77
Uncharacterized protein C17orf77; Chromosome 17 open reading frame 77 (243 aa)
           
  0.670
C15orf52
Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 (534 aa)
           
  0.658
LOC81691
Putative RNA exonuclease NEF-sp (774 aa)
           
  0.586
TBC1D31
TBC1 domain family member 31; WD repeat domain containing (1066 aa)
           
  0.540
STK32B
Serine/threonine kinase 32B (414 aa)
           
  0.530
TTC28
Tetratricopeptide repeat protein 28; During mitosis, may be involved in the condensation of spindle midzone microtubules, leading to the formation of midbody; Tetratricopeptide repeat domain containing (2481 aa)
     
   
  0.504
FAM20A
Pseudokinase FAM20A; Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the ’matrix’ that guides the deposition of the enamel minerals (541 aa)
           
  0.473
NDST4
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity (By similarity); Belongs to the sulfotransferase 1 family. NDST subfamily (872 aa)
           
  0.430
DERL2
Derlin-2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and misfolded glycoproteins. May also be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the [...] (239 aa)
     
   
  0.427
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif 17 (1095 aa)
           
  0.426
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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