node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP9A | DOPEY1 | ENSP00000342481 | ENSP00000237163 | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | 0.664 |
ATP9A | DOPEY2 | ENSP00000342481 | ENSP00000382104 | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family | 0.545 |
ATP9A | ITFG1 | ENSP00000342481 | ENSP00000319918 | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | 0.636 |
ATP9A | MON2 | ENSP00000342481 | ENSP00000377250 | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | 0.748 |
ATP9A | MYO1G | ENSP00000342481 | ENSP00000258787 | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | Unconventional myosin-Ig; Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T- cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication. Also required in B- cells, where it regulates different membrane/cytoskeleton- dependent proce [...] | 0.562 |
ATP9A | NEO1 | ENSP00000342481 | ENSP00000341198 | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | Neogenin; Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response; Belongs to the immunoglobulin superfamily. DCC family | 0.578 |
ATP9A | TMEM30A | ENSP00000342481 | ENSP00000230461 | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | Cell cycle control protein 50A; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2-TMEM30A flippase complex. [...] | 0.771 |
ATP9A | TMEM30B | ENSP00000342481 | ENSP00000450842 | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | Cell cycle control protein 50B; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to th [...] | 0.655 |
ATP9A | TMEM30C | ENSP00000342481 | ENSP00000419663 | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | Cell cycle control protein 50C; Transmembrane protein 30C; Belongs to the CDC50/LEM3 family | 0.707 |
ATP9A | ZFP64 | ENSP00000342481 | ENSP00000216923 | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | Zinc finger protein 64 homolog, isoforms 1 and 2; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.706 |
DOPEY1 | ATP9A | ENSP00000237163 | ENSP00000342481 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | 0.664 |
DOPEY1 | MON2 | ENSP00000237163 | ENSP00000377250 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | 0.923 |
DOPEY2 | ATP9A | ENSP00000382104 | ENSP00000342481 | Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | 0.545 |
DOPEY2 | MON2 | ENSP00000382104 | ENSP00000377250 | Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | 0.858 |
ITFG1 | ATP9A | ENSP00000319918 | ENSP00000342481 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | 0.636 |
MON2 | ATP9A | ENSP00000377250 | ENSP00000342481 | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | 0.748 |
MON2 | DOPEY1 | ENSP00000377250 | ENSP00000237163 | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | 0.923 |
MON2 | DOPEY2 | ENSP00000377250 | ENSP00000382104 | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family | 0.858 |
MON2 | NEO1 | ENSP00000377250 | ENSP00000341198 | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | Neogenin; Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response; Belongs to the immunoglobulin superfamily. DCC family | 0.425 |
MON2 | TMEM30C | ENSP00000377250 | ENSP00000419663 | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | Cell cycle control protein 50C; Transmembrane protein 30C; Belongs to the CDC50/LEM3 family | 0.420 |