• Version:
  • 11.0 [archived version]
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ARL15 ARL15 IFT74 IFT74 CCDC138 CCDC138 TTC30A TTC30A IFT52 IFT52 ANKRD55 ANKRD55 WDR90 WDR90 TTC30B TTC30B IFT46 IFT46 KIAA1328 KIAA1328 C5orf30 C5orf30
"ANKRD55" - Ankyrin repeat domain-containing protein 55 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ANKRD55Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing (614 aa)    
Predicted Functional Partners:
IFT52
Intraflagellar transport protein 52 homolog; Involved in ciliogenesis as part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Required for the anterograde transport of IFT88 (437 aa)
       
 
  0.895
IFT46
Intraflagellar transport proteins; Cilia and flagella associated (355 aa)
       
 
  0.843
IFT74
Intraflagellar transport protein 74 homolog; Component of the intraflagellar transport (IFT) complex B- together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis; Belongs to the IFT74 family (600 aa)
     
 
  0.838
WDR90
WD repeat-containing protein 90; WD repeat domain containing (1748 aa)
     
 
  0.744
KIAA1328
Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes (577 aa)
           
  0.723
CCDC138
Coiled-coil domain containing 138 (665 aa)
           
  0.718
TTC30A
Tetratricopeptide repeat protein 30A; Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (665 aa)
       
      0.696
TTC30B
Tetratricopeptide repeat protein 30B; Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (665 aa)
       
      0.691
C5orf30
UNC119-binding protein C5orf30; Probably plays a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters- may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B. May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells (206 aa)
           
  0.669
ARL15
ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family (204 aa)
     
 
  0.612
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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