• Version:
  • 11.0 [archived version]
STRINGSTRING
ASL ASL ASS1 ASS1 NAGS NAGS OTC OTC OAT OAT XKRX XKRX SLC25A15 SLC25A15 SLC7A10 SLC7A10 OGG1 OGG1 PLOD1 PLOD1 GRN GRN
"SLC25A15" - Mitochondrial ornithine transporter 1 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
SLC25A15Mitochondrial ornithine transporter 1; Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix; Solute carriers (301 aa)    
Predicted Functional Partners:
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1; Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (By similarity). Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (Probable) (727 aa)
           
  0.670
OTC
Ornithine carbamoyltransferase, mitochondrial; Ornithine carbamoyltransferase; Belongs to the ATCase/OTCase family (354 aa)
     
   
  0.643
NAGS
N-acetylglutamate synthase, mitochondrial; Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity; Belongs to the acetyltransferase family (534 aa)
     
   
  0.604
OGG1
N-glycosylase/DNA lyase; DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta- lyase activity that nicks DNA 3’ to the lesion; Belongs to the type-1 OGG1 family (424 aa)
           
  0.576
SLC7A10
Asc-type amino acid transporter 1; Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse; Belongs to the amino acid-polyamine-organocation (APC) superfamily (523 aa)
           
  0.574
GRN
Granulins; Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling (593 aa)
           
  0.570
ASS1
Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. Type 1 subfamily (412 aa)
     
   
  0.564
OAT
Ornithine aminotransferase, mitochondrial; Ornithine aminotransferase (439 aa)
     
   
  0.551
ASL
Argininosuccinate lyase (464 aa)
     
   
  0.549
XKRX
XK-related protein 2; XK related, X-linked (449 aa)
           
  0.542
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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