• Version:
  • 11.0 [archived version]
STRINGSTRING
WDR83OS WDR83OS T T SDCCAG3 SDCCAG3 CHRD CHRD C15orf61 C15orf61 SKOR1 SKOR1 IQCH IQCH MAP2K5 MAP2K5
"C15orf61" - Uncharacterized protein C15orf61 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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C15orf61Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61 (157 aa)    
Predicted Functional Partners:
SKOR1
SKI family transcriptional corepressor 1; Acts as a transcriptional corepressor of LBX1 (By similarity). Inhibits BMP signaling; SKI transcriptional corepressors (868 aa)
           
  0.582
T
Brachyury protein; Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site (435 aa)
           
  0.452
SDCCAG3
Serologically defined colon cancer antigen 3; May be involved in modulation of TNF response. May be involved in presentation of TNFRSF1A on the cell surface (By similarity). Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1 (435 aa)
           
  0.442
IQCH
IQ domain-containing protein H; May play a regulatory role in spermatogenesis (1027 aa)
 
 
        0.441
MAP2K5
Dual specificity mitogen-activated protein kinase kinase 5; Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily (448 aa)
     
   
  0.418
WDR83OS
Protein Asterix; WD repeat domain 83 opposite strand (106 aa)
           
  0.405
CHRD
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity) (955 aa)
           
  0.405
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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