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  • 11.0 [archived version]
STRINGSTRING
LPHN3 LPHN3 ETV3L ETV3L RBMXL3 RBMXL3 ACTRT3 ACTRT3 LRRIQ4 LRRIQ4 LRRC34 LRRC34 MYNN MYNN KIAA1671 KIAA1671 LRRC31 LRRC31 LPHN1 LPHN1 LPHN2 LPHN2
"LRRIQ4" - Leucine rich repeats and IQ motif containing 4 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
LRRIQ4Leucine rich repeats and IQ motif containing 4 (560 aa)    
Predicted Functional Partners:
LRRC34
Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro (464 aa)
     
   
  0.762
ACTRT3
Actin related protein T3 (372 aa)
       
 
  0.750
LPHN3
Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily (1469 aa)
     
      0.685
LPHN1
Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) (1474 aa)
     
      0.685
LPHN2
Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily (1403 aa)
     
      0.685
MYNN
Myoneurin; Zinc fingers C2H2-type; BTB domain containing (610 aa)
       
 
  0.679
RBMXL3
RNA binding motif protein, X-linked like 3 (1067 aa)
           
  0.678
ETV3L
ETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family (361 aa)
           
  0.585
LRRC31
Leucine-rich repeat-containing protein 31; Leucine rich repeat containing 31 (552 aa)
     
   
  0.565
KIAA1671
Uncharacterized protein KIAA1671; KIAA1671 (1806 aa)
           
  0.543
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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