node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTRT3 | LRRC34 | ENSP00000333037 | ENSP00000414635 | Actin related protein T3 | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro | 0.683 |
ACTRT3 | LRRIQ4 | ENSP00000333037 | ENSP00000342188 | Actin related protein T3 | Leucine rich repeats and IQ motif containing 4 | 0.750 |
ACTRT3 | MYNN | ENSP00000333037 | ENSP00000326240 | Actin related protein T3 | Myoneurin; Zinc fingers C2H2-type; BTB domain containing | 0.704 |
ETV3L | LRRIQ4 | ENSP00000430271 | ENSP00000342188 | ETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family | Leucine rich repeats and IQ motif containing 4 | 0.585 |
ETV3L | RBMXL3 | ENSP00000430271 | ENSP00000417451 | ETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family | RNA binding motif protein, X-linked like 3 | 0.705 |
KIAA1671 | LRRIQ4 | ENSP00000351207 | ENSP00000342188 | Uncharacterized protein KIAA1671; KIAA1671 | Leucine rich repeats and IQ motif containing 4 | 0.543 |
LPHN1 | LRRIQ4 | ENSP00000340688 | ENSP00000342188 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | Leucine rich repeats and IQ motif containing 4 | 0.685 |
LPHN2 | LRRIQ4 | ENSP00000322270 | ENSP00000342188 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | Leucine rich repeats and IQ motif containing 4 | 0.685 |
LPHN3 | LRRIQ4 | ENSP00000422533 | ENSP00000342188 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | Leucine rich repeats and IQ motif containing 4 | 0.685 |
LRRC31 | LRRC34 | ENSP00000325978 | ENSP00000414635 | Leucine-rich repeat-containing protein 31; Leucine rich repeat containing 31 | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro | 0.671 |
LRRC31 | LRRIQ4 | ENSP00000325978 | ENSP00000342188 | Leucine-rich repeat-containing protein 31; Leucine rich repeat containing 31 | Leucine rich repeats and IQ motif containing 4 | 0.565 |
LRRC31 | MYNN | ENSP00000325978 | ENSP00000326240 | Leucine-rich repeat-containing protein 31; Leucine rich repeat containing 31 | Myoneurin; Zinc fingers C2H2-type; BTB domain containing | 0.542 |
LRRC34 | ACTRT3 | ENSP00000414635 | ENSP00000333037 | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro | Actin related protein T3 | 0.683 |
LRRC34 | LRRC31 | ENSP00000414635 | ENSP00000325978 | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro | Leucine-rich repeat-containing protein 31; Leucine rich repeat containing 31 | 0.671 |
LRRC34 | LRRIQ4 | ENSP00000414635 | ENSP00000342188 | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro | Leucine rich repeats and IQ motif containing 4 | 0.762 |
LRRC34 | MYNN | ENSP00000414635 | ENSP00000326240 | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro | Myoneurin; Zinc fingers C2H2-type; BTB domain containing | 0.671 |
LRRIQ4 | ACTRT3 | ENSP00000342188 | ENSP00000333037 | Leucine rich repeats and IQ motif containing 4 | Actin related protein T3 | 0.750 |
LRRIQ4 | ETV3L | ENSP00000342188 | ENSP00000430271 | Leucine rich repeats and IQ motif containing 4 | ETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family | 0.585 |
LRRIQ4 | KIAA1671 | ENSP00000342188 | ENSP00000351207 | Leucine rich repeats and IQ motif containing 4 | Uncharacterized protein KIAA1671; KIAA1671 | 0.543 |
LRRIQ4 | LPHN1 | ENSP00000342188 | ENSP00000340688 | Leucine rich repeats and IQ motif containing 4 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | 0.685 |