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STRINGSTRING
C1orf194 C1orf194 FAM102B FAM102B AKNAD1 AKNAD1 CLCC1 CLCC1 FNDC7 FNDC7 WDR47 WDR47 TMEM167B TMEM167B ZPBP2 ZPBP2 TAF13 TAF13 TRAPPC6B TRAPPC6B SNX14 SNX14
"TMEM167B" - Protein kish-B in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
TMEM167BProtein kish-B; Involved in the early part of the secretory pathway (74 aa)    
Predicted Functional Partners:
SNX14
Sorting nexin-14; Plays a role in maintaining normal neuronal excitability and synaptic transmission. May be involved in several stages of intracellular trafficking (By similarity). Required for autophagosome clearance, possibly by mediating the fusion of lysosomes with autophagosomes (Probable). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes. Does not bind phosphatidylinositol 3-phosphate (PtdIns(3P)); Sorting nexins (946 aa)
      
   
  0.687
TRAPPC6B
Trafficking protein particle complex subunit 6B; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Trafficking protein particle complex (158 aa)
            
  0.684
FNDC7
Fibronectin type III domain containing 7 (733 aa)
            
  0.641
CLCC1
Chloride channel CLIC-like protein 1; Seems to act as a chloride ion channel; Tetraspan junctional complex superfamily (551 aa)
            
  0.615
FAM102B
Protein FAM102B; Family with sequence similarity 102 member B; NT-C2 domain containing (360 aa)
            
  0.576
AKNAD1
Protein AKNAD1; AKNA domain containing 1 (836 aa)
            
  0.566
WDR47
WD repeat-containing protein 47; WD repeat domain containing (927 aa)
            
  0.559
C1orf194
Uncharacterized protein C1orf194; Chromosome 1 open reading frame 194 (157 aa)
            
  0.551
TAF13
Transcription initiation factor TFIID subunit 13; Component of the DNA-binding general RNA polymerase II transcription factor IID complex (TFIID). TFIID plays a critical role in the regulation of gene transcription in eukaryotic cells; Belongs to the TAF13 family (124 aa)
      
   
  0.546
ZPBP2
Zona pellucida-binding protein 2; Is implicated in sperm-oocyte interaction during fertilization; Immunoglobulin like domain containing (338 aa)
            
  0.541
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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