FOXD4L3 protein (human) - STRING database

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Score

FOXD4L3

Forkhead box D4 like 3 (417 aa)

Predicted Functional Partners:

ANKRD20A2

0.684

FOXR2

0.587

ZNF812

0.585

ZNF595

0.532

ARHGEF5

0.406

NDUFV3

0.402

MYO18B

0.400

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD20A2	ARHGEF5	ENSP00000366826	ENSP00000056217	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	Rho guanine nucleotide exchange factor 5; Guanine nucleotide exchange factor which activates Rho GTPases. Strongly activates RHOA. Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization. Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia. Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration [...]	0.477
ANKRD20A2	FOXD4L3	ENSP00000366826	ENSP00000341961	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	Forkhead box D4 like 3	0.684
ANKRD20A2	MYO18B	ENSP00000366826	ENSP00000334563	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family	0.505
ANKRD20A2	ZNF595	ENSP00000366826	ENSP00000477392	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.596
ANKRD20A2	ZNF812	ENSP00000366826	ENSP00000395629	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	Zinc finger protein 812	0.659
ARHGEF5	ANKRD20A2	ENSP00000056217	ENSP00000366826	Rho guanine nucleotide exchange factor 5; Guanine nucleotide exchange factor which activates Rho GTPases. Strongly activates RHOA. Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization. Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia. Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration [...]	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	0.477
ARHGEF5	FOXD4L3	ENSP00000056217	ENSP00000341961	Rho guanine nucleotide exchange factor 5; Guanine nucleotide exchange factor which activates Rho GTPases. Strongly activates RHOA. Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization. Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia. Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration [...]	Forkhead box D4 like 3	0.406
FOXD4L3	ANKRD20A2	ENSP00000341961	ENSP00000366826	Forkhead box D4 like 3	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	0.684
FOXD4L3	ARHGEF5	ENSP00000341961	ENSP00000056217	Forkhead box D4 like 3	Rho guanine nucleotide exchange factor 5; Guanine nucleotide exchange factor which activates Rho GTPases. Strongly activates RHOA. Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization. Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia. Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration [...]	0.406
FOXD4L3	FOXR2	ENSP00000341961	ENSP00000427329	Forkhead box D4 like 3	Forkhead box R2	0.587
FOXD4L3	MYO18B	ENSP00000341961	ENSP00000334563	Forkhead box D4 like 3	Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family	0.400
FOXD4L3	NDUFV3	ENSP00000341961	ENSP00000346196	Forkhead box D4 like 3	NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I	0.402
FOXD4L3	ZNF595	ENSP00000341961	ENSP00000477392	Forkhead box D4 like 3	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.532
FOXD4L3	ZNF812	ENSP00000341961	ENSP00000395629	Forkhead box D4 like 3	Zinc finger protein 812	0.585
FOXR2	FOXD4L3	ENSP00000427329	ENSP00000341961	Forkhead box R2	Forkhead box D4 like 3	0.587
MYO18B	ANKRD20A2	ENSP00000334563	ENSP00000366826	Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	0.505
MYO18B	FOXD4L3	ENSP00000334563	ENSP00000341961	Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family	Forkhead box D4 like 3	0.400
NDUFV3	FOXD4L3	ENSP00000346196	ENSP00000341961	NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I	Forkhead box D4 like 3	0.402
ZNF595	ANKRD20A2	ENSP00000477392	ENSP00000366826	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	0.596
ZNF595	FOXD4L3	ENSP00000477392	ENSP00000341961	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Forkhead box D4 like 3	0.532

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