node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP13A5 | ATPAF1 | ENSP00000341942 | ENSP00000460964 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | ATP synthase mitochondrial F1 complex assembly factor 1; May play an essential role for the assembly of the mitochondrial F1-F0 complex | 0.556 |
ATP13A5 | C3orf20 | ENSP00000341942 | ENSP00000253697 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | Uncharacterized protein C3orf20; Chromosome 3 open reading frame 20 | 0.714 |
ATP13A5 | CDH19 | ENSP00000341942 | ENSP00000262150 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | Cadherin-19; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | 0.511 |
ATP13A5 | CLDN17 | ENSP00000341942 | ENSP00000286808 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | Claudin-17; Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability; Belongs to the claudin family | 0.499 |
ATP13A5 | FAM186A | ENSP00000341942 | ENSP00000329995 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | Protein FAM186A; Family with sequence similarity 186 member A; Belongs to the FAM186 family | 0.473 |
ATP13A5 | GDF2 | ENSP00000341942 | ENSP00000463051 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | Growth/differentiation factor 2; Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG | 0.462 |
ATP13A5 | ITGB1BP1 | ENSP00000341942 | ENSP00000353850 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | Integrin beta-1-binding protein 1; Key regulator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1. Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis. Stimulates cellular proliferation in a fibronectin- dependent manner. Involved in the regulation of beta-1 integrin- containing focal adhesion (FA) site dynamics by controlli [...] | 0.538 |
ATP13A5 | OR8U1 | ENSP00000341942 | ENSP00000304188 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | Olfactory receptor 8U1; Odorant receptor; Olfactory receptors, family 8 | 0.587 |
ATP13A5 | PRRT3 | ENSP00000341942 | ENSP00000392511 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | Proline rich transmembrane protein 3 | 0.605 |
ATP13A5 | ZW10 | ENSP00000341942 | ENSP00000200135 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assemb [...] | 0.459 |
ATPAF1 | ATP13A5 | ENSP00000460964 | ENSP00000341942 | ATP synthase mitochondrial F1 complex assembly factor 1; May play an essential role for the assembly of the mitochondrial F1-F0 complex | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | 0.556 |
C3orf20 | ATP13A5 | ENSP00000253697 | ENSP00000341942 | Uncharacterized protein C3orf20; Chromosome 3 open reading frame 20 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | 0.714 |
C3orf20 | GDF2 | ENSP00000253697 | ENSP00000463051 | Uncharacterized protein C3orf20; Chromosome 3 open reading frame 20 | Growth/differentiation factor 2; Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG | 0.516 |
C3orf20 | OR8U1 | ENSP00000253697 | ENSP00000304188 | Uncharacterized protein C3orf20; Chromosome 3 open reading frame 20 | Olfactory receptor 8U1; Odorant receptor; Olfactory receptors, family 8 | 0.723 |
CDH19 | ATP13A5 | ENSP00000262150 | ENSP00000341942 | Cadherin-19; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | 0.511 |
CDH19 | ITGB1BP1 | ENSP00000262150 | ENSP00000353850 | Cadherin-19; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | Integrin beta-1-binding protein 1; Key regulator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1. Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis. Stimulates cellular proliferation in a fibronectin- dependent manner. Involved in the regulation of beta-1 integrin- containing focal adhesion (FA) site dynamics by controlli [...] | 0.491 |
CLDN17 | ATP13A5 | ENSP00000286808 | ENSP00000341942 | Claudin-17; Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability; Belongs to the claudin family | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | 0.499 |
FAM186A | ATP13A5 | ENSP00000329995 | ENSP00000341942 | Protein FAM186A; Family with sequence similarity 186 member A; Belongs to the FAM186 family | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | 0.473 |
GDF2 | ATP13A5 | ENSP00000463051 | ENSP00000341942 | Growth/differentiation factor 2; Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily | 0.462 |
GDF2 | C3orf20 | ENSP00000463051 | ENSP00000253697 | Growth/differentiation factor 2; Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG | Uncharacterized protein C3orf20; Chromosome 3 open reading frame 20 | 0.516 |