• Version:
  • 11.0 [archived version]
STRINGSTRING
FAM186A FAM186A PRRT3 PRRT3 ATPAF1 ATPAF1 C3orf20 C3orf20 ATP13A5 ATP13A5 GDF2 GDF2 ZW10 ZW10 ITGB1BP1 ITGB1BP1 OR8U1 OR8U1 CDH19 CDH19 CLDN17 CLDN17
"ATP13A5" - Probable cation-transporting ATPase 13A5 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ATP13A5Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily (1218 aa)    
Predicted Functional Partners:
C3orf20
Uncharacterized protein C3orf20; Chromosome 3 open reading frame 20 (904 aa)
           
  0.714
PRRT3
Proline rich transmembrane protein 3 (981 aa)
     
        0.605
OR8U1
Olfactory receptor 8U1; Odorant receptor; Olfactory receptors, family 8 (309 aa)
           
  0.587
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1; May play an essential role for the assembly of the mitochondrial F1-F0 complex (351 aa)
     
   
  0.556
ITGB1BP1
Integrin beta-1-binding protein 1; Key regulator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1. Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis. Stimulates cellular proliferation in a fibronectin- dependent manner. Involved in the regulation of beta-1 integrin- containing focal adhesion (FA) site dynamics by controlli [...] (200 aa)
           
  0.538
CDH19
Cadherin-19; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (772 aa)
     
   
  0.511
CLDN17
Claudin-17; Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability; Belongs to the claudin family (224 aa)
           
  0.499
FAM186A
Protein FAM186A; Family with sequence similarity 186 member A; Belongs to the FAM186 family (2351 aa)
           
  0.473
GDF2
Growth/differentiation factor 2; Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG (429 aa)
     
   
  0.462
ZW10
Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assemb [...] (779 aa)
           
  0.459
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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