• Version:
  • 11.0 [archived version]
STRINGSTRING
RPS3 RPS3 RPS13 RPS13 RPS8 RPS8 RPS14 RPS14 RPL6 RPL6 RPLP0 RPLP0 RPL8 RPL8 RPL18A RPL18A RPS4X RPS4X RPS2 RPS2 RPL4 RPL4
"RPS2" - Ribosomal protein S2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPS2Ribosomal protein S2 (293 aa)    
Predicted Functional Partners:
RPS4X
Ribosomal protein S4, X-linked; Belongs to the eukaryotic ribosomal protein eS4 family (263 aa)
   
  0.999
RPS8
Ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family (208 aa)
      
  0.999
RPL4
L ribosomal proteins (427 aa)
 
  0.999
RPS3
40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protein [...] (259 aa)
 
  0.999
RPS13
Ribosomal protein S13 (151 aa)
    
  0.999
RPLP0
60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10 (317 aa)
   
  0.999
RPS14
Ribosomal protein S14 (151 aa)
 
  0.999
RPL6
60S ribosomal protein L6; Component of the large ribosomal subunit (288 aa)
   
  0.999
RPL18A
Ribosomal protein L18a (176 aa)
      
  0.999
RPL8
60S ribosomal protein L8; Component of the large ribosomal subunit (257 aa)
 
  0.999
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >